Gut Homeostasis: Active Migration of Intestinal Epithelial Cells in Tissue Renewal
Sign Up to like & getrecommendations! Published in 2019 at "Current Biology"
DOI: 10.1016/j.cub.2019.08.068
Abstract: A new study has uncovered a previously unknown feature of intestinal epithelial cells during gut homeostasis. Biophysical modeling combined with quantitative tissue imaging indicates that epithelial cells actively migrate up the gut villus, challenging the… read more here.
Keywords: epithelial cells; intestinal epithelial; tissue renewal; tissue ... See more keywords
The Production and Function of Endogenous Interleukin-10 in Intestinal Epithelial Cells and Gut Homeostasis
Sign Up to like & getrecommendations! Published in 2021 at "Cellular and Molecular Gastroenterology and Hepatology"
DOI: 10.1016/j.jcmgh.2021.07.005
Abstract: The healthy gut is achieved and maintained through a balanced relationship between the mucosal immune system, microbial communities resident in the lumen, and the intestinal epithelium. The intestinal epithelium plays an exceptionally important role in… read more here.
Keywords: homeostasis; epithelial cells; intestinal epithelial; gut homeostasis ... See more keywords
Human gut homeostasis and regeneration: the role of the gut microbiota and its metabolites.
Sign Up to like & getrecommendations! Published in 2022 at "Critical reviews in microbiology"
DOI: 10.1080/1040841x.2022.2142088
Abstract: The healthy human gut is a balanced ecosystem where host cells and representatives of the gut microbiota interact and communicate in a bidirectional manner at the gut epithelium. As a result of these interactions, many… read more here.
Keywords: gut; human gut; gut homeostasis; microbiota metabolites ... See more keywords
HP1c regulates development and gut homeostasis by suppressing Notch signaling through Su(H)
Sign Up to like & getrecommendations! Published in 2021 at "EMBO reports"
DOI: 10.15252/embr.202051298
Abstract: Notch signaling and epigenetic factors are known to play critical roles in regulating tissue homeostasis in most multicellular organisms, but how Notch signaling coordinates with epigenetic modulators to control differentiation remains poorly understood. Here, we… read more here.
Keywords: gut homeostasis; notch signaling; hp1c;
Methamphetamine Disturbs Gut Homeostasis and Reshapes Serum Metabolome, Inducing Neurotoxicity and Abnormal Behaviors in Mice
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2022.755189
Abstract: As an illicit psychostimulant, repeated methamphetamine (MA) exposure results in addiction and causes severe neurotoxicity. Studies have revealed complex interactions among gut homeostasis, metabolism, and the central nervous system (CNS). To investigate the disturbance of… read more here.
Keywords: gut homeostasis; behaviors mice; neurotoxicity; serum metabolome ... See more keywords
Intestinal ELF4 Deletion Exacerbates Alcoholic Liver Disease by Disrupting Gut Homeostasis
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23094825
Abstract: Alcohol liver disease (ALD) is characterized by intestinal barrier disruption and gut dysbiosis. Dysfunction of E74-like ETS transcription factor 4 (ELF4) leads to colitis. We aimed to test the hypothesis that intestinal ELF4 plays a… read more here.
Keywords: elf4 mice; gut homeostasis; elf4; intestinal elf4 ... See more keywords
Gut homeostasis, injury, and healing: New therapeutic targets
Sign Up to like & getrecommendations! Published in 2022 at "World Journal of Gastroenterology"
DOI: 10.3748/wjg.v28.i17.1725
Abstract: The integrity of the gastrointestinal mucosa plays a crucial role in gut homeostasis, which depends upon the balance between mucosal injury by destructive factors and healing via protective factors. The persistence of noxious agents such… read more here.
Keywords: new therapeutic; gut homeostasis; mucosal; injury ... See more keywords