The duodenal mucosa associated microbiome, visceral sensory function, immune activation and psychological comorbidities in functional gastrointestinal disorders with and without self-reported non-celiac wheat sensitivity
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DOI: 10.1080/19490976.2022.2132078
Abstract: ABSTRACT Frequently, patients with functional gastrointestinal disorders (FGIDs) report intolerance of wheat products. We compared gastrointestinal symptoms, sensory function, psychiatric comorbidities, gut-homing immune cells, and duodenal mucosa-associated microbiome (d-MAM) in FGID patients and controls with… read more here.
Keywords: fgid patients; function; functional gastrointestinal; gut homing ... See more keywords
Gut-homing CD4+ T cells are associated with the activity of gastritis in HIV-infected adults.
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DOI: 10.1089/aid.2020.0086
Abstract: OBJECTIVES Previous studies had shown that HIV-infected individuals were less susceptible to chronic gastritis and Helicobacter pylori (H. pylori) infection. Th1 and Th17 cells are important components of the immune response to H. pylori in… read more here.
Keywords: homing cd4; pylori; hiv infected; gastritis ... See more keywords
Imprinting of Gut-Homing Receptors on Mtb-Specific Th1* Cells Is Associated with Reduced Lung Homing after Gavage BCG Vaccination of Rhesus Macaques
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DOI: 10.1128/mbio.00220-23
Abstract: Mycobacterium tuberculosis (Mtb) is a leading cause of global infectious disease mortality. The vaccine for Mtb, Bacillus Calmette-Guérin (BCG), was originally developed as an oral vaccine, but is now given intradermally. ABSTRACT Alternative delivery routes… read more here.
Keywords: vaccination; bcg vaccination; gut homing; bcg ... See more keywords
Non-classical monocyte homing to the gut via α4β7 integrin mediates macrophage-dependent intestinal wound healing
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DOI: 10.1136/gutjnl-2018-316772
Abstract: Objective To study the role of α4β7 integrin for gut homing of monocytes and to explore the biological consequences of therapeutic α4β7 inhibition with regard to intestinal wound healing. Design We studied the expression of… read more here.
Keywords: wound healing; integrin; non classical; intestinal wound ... See more keywords