Will medications that mimic gut hormones or target their receptors eventually replace bariatric surgery?
Sign Up to like & getrecommendations! Published in 2019 at "Metabolism: clinical and experimental"
DOI: 10.1016/j.metabol.2019.153960
Abstract: Bariatric surgery is currently the most effective therapeutic modality through which sustained beneficial effects on weight loss and metabolic improvement are achieved. During recent years, indications for bariatric surgery have been expanded to include cases… read more here.
Keywords: surgery; gut hormones; gut peptide; mimic gut ... See more keywords
Acute exposure to a hot ambient temperature reduces energy intake but does not affect gut hormones in men during rest
Sign Up to like & getrecommendations! Published in 2020 at "British Journal of Nutrition"
DOI: 10.1017/s0007114520002792
Abstract: Abstract This study examined the effect of ambient temperature on energy intake, perceived appetite and gut hormone responses during rest in men. Thirteen men (age 21·5 (sd 1·4) years; BMI 24·7 (sd 2·2) kg/m2) completed… read more here.
Keywords: gut hormones; energy; ambient temperature; energy intake ... See more keywords
Gut hormones involved in bone remodelling
Sign Up to like & getrecommendations! Published in 2020 at "Nature Reviews Endocrinology"
DOI: 10.1038/s41574-020-0354-8
Abstract: Gut hormones seem to regulate bone metabolism, but the mechanisms are unclear. New research suggests that glucose-dependent insulinotropic polypeptide (GIP) and xenin (hormones secreted by enteroendocrine K cells) are key factors in regulating several aspects… read more here.
Keywords: gut hormones; bone; physiology; gip ... See more keywords
Novel approaches to anti-obesity drug discovery with gut hormones over the past 10 years
Sign Up to like & getrecommendations! Published in 2019 at "Expert Opinion on Drug Discovery"
DOI: 10.1080/17460441.2019.1646243
Abstract: ABSTRACT Introduction: Obesity is a global pandemic and new pharmacotherapies which combine weight loss efficacy, long-term safety, and reversal of metabolic co-morbidities are sorely needed. Gut hormones play key roles in regulating satiety and metabolism,… read more here.
Keywords: drug discovery; gut; anti obesity; gut hormones ... See more keywords
Liraglutide changes postprandial responses of gut hormones involved in the regulation of gallbladder motility
Sign Up to like & getrecommendations! Published in 2023 at "Diabetes"
DOI: 10.1111/dom.15017
Abstract: Liraglutide treatment is associated with gallbladder‐related disorders and has been shown to delay postprandial gallbladder refilling. The gut hormones cholecystokinin (CCK), fibroblast growth factor 19 (FGF19) and glucagon‐like peptide 2 (GLP‐2), are known to regulate… read more here.
Keywords: liraglutide changes; gut hormones; gallbladder; gallbladder motility ... See more keywords
Gut Hormones Secretion across Clusters of Metabolic Syndrome in Prepubertal Children with Obesity
Sign Up to like & getrecommendations! Published in 2022 at "Hormone Research in Paediatrics"
DOI: 10.1159/000524830
Abstract: Introduction: Metabolic Syndrome (MetS) represents a common dysmetabolic state in children with obesity. Although data in youth show a role of gut hormones (GH) in the risk of developing MetS, no data are available during… read more here.
Keywords: metabolic syndrome; children obesity; gut hormones; obesity ... See more keywords
Pancreatic and gut hormones as predictors of new-onset prediabetes after non-necrotising acute pancreatitis: a prospective longitudinal cohort study
Sign Up to like & getrecommendations! Published in 2021 at "Endocrine Connections"
DOI: 10.1530/ec-21-0229
Abstract: Objective Early identification of individuals at high risk for metabolic derangements after an attack of acute pancreatitis (AP) is critical with a view to tertiary preventing of this disease. The aim was to investigate whether… read more here.
Keywords: acute pancreatitis; pancreatic gut; gut hormones; study ... See more keywords
Glucose- and Bile Acid-Stimulated Secretion of Gut Hormones in the Isolated Perfused Intestine Is Not Impaired in Diet-Induced Obese Mice
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2022.884501
Abstract: Purpose Decreased circulating levels of food-intake-regulating gut hormones have been observed in type 2 diabetes and obesity. However, it is still unknown if this is due to decreased secretion from the gut mucosal cells or… read more here.
Keywords: glucose bile; dio mice; secretion; gut hormones ... See more keywords
Gut Hormones as Potential Therapeutic Targets or Biomarkers of Response in Depression: The Case of Motilin
Sign Up to like & getrecommendations! Published in 2021 at "Life"
DOI: 10.3390/life11090892
Abstract: Recent research has identified the gut–brain axis as a key mechanistic pathway and potential therapeutic target in depression. In this paper, the potential role of gut hormones as potential treatments or predictors of response in… read more here.
Keywords: motilin; depression; gut hormones; hormones potential ... See more keywords
Gut Hormones in Health and Obesity: The Upcoming Role of Short Chain Fatty Acids
Sign Up to like & getrecommendations! Published in 2021 at "Nutrients"
DOI: 10.3390/nu13020481
Abstract: We are currently facing an obesity pandemic, with worldwide obesity rates having tripled since 1975. Obesity is one of the main risk factors for the development of non-communicable diseases, which are now the leading cause… read more here.
Keywords: gut hormones; fatty acids; role short; short chain ... See more keywords
Association of Gut Hormones and Microbiota with Vascular Dysfunction in Obesity
Sign Up to like & getrecommendations! Published in 2021 at "Nutrients"
DOI: 10.3390/nu13020613
Abstract: In the past few decades, obesity has reached pandemic proportions. Obesity is among the main risk factors for cardiovascular diseases, since chronic fat accumulation leads to dysfunction in vascular endothelium and to a precocious arterial… read more here.
Keywords: gut hormones; dysfunction; hormones microbiota; association gut ... See more keywords