The spinal cord-gut-immune axis as a master regulator of health and neurological function after spinal cord injury
Sign Up to like & getrecommendations! Published in 2020 at "Experimental Neurology"
DOI: 10.1016/j.expneurol.2019.113085
Abstract: Most spinal cord injury (SCI) research programs focus only on the injured spinal cord with the goal of restoring locomotor function by overcoming mechanisms of cell death or axon regeneration failure. Given the importance of… read more here.
Keywords: cord; immune axis; cord gut; gut immune ... See more keywords
Structure-function relationship and impact on the gut-immune barrier function of non-digestible carbohydrates and human milk oligosaccharides applicable for infant formula.
Sign Up to like & getrecommendations! Published in 2023 at "Critical reviews in food science and nutrition"
DOI: 10.1080/10408398.2023.2199072
Abstract: Human milk oligosaccharides (hMOs) in mothers' milk play a crucial role in guiding the colonization of microbiota and gut-immune barrier development in infants. Non-digestible carbohydrates (NDCs) such as synthetic single hMOs, galacto-oligosaccharides (GOS), inulin-type fructans… read more here.
Keywords: human milk; function; gut; gut immune ... See more keywords
Gut immune homeostasis: the immunomodulatory role of Bacillus clausii, from basic to clinical evidence
Sign Up to like & getrecommendations! Published in 2022 at "Expert Review of Clinical Immunology"
DOI: 10.1080/1744666x.2022.2085559
Abstract: ABSTRACT Introduction The gut microbiota affects the development of the gut immune system in early life. Perturbations to microbiota structure and composition during this period can have long-term consequences on the health of the individual,… read more here.
Keywords: gut; clinical evidence; gut immune; bacillus clausii ... See more keywords
The spinal cord-gut-immune axis and its implications on therapeutic development for spinal cord injury.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of neurotrauma"
DOI: 10.1089/neu.2022.0264
Abstract: Spinal cord injury (SCI) affects approximately 1.3 million people living in the United States. Most research efforts have been focused on reversing paralysis, as this is arguably the most defining feature of SCI. The damage… read more here.
Keywords: cord; immune axis; cord gut; gut immune ... See more keywords
Novel “Thetis” antigen‐presenting cells promote early life gut immune tolerance
Sign Up to like & getrecommendations! Published in 2022 at "Immunology and Cell Biology"
DOI: 10.1111/imcb.12605
Abstract: With inflammatory bowel disease, such as Crohn’s disease and colitis, being heavily dependent on immune cell function, the mechanisms controlling aberrant immune cell activity in the gut have become an area of interest for biomedical… read more here.
Keywords: immune tolerance; gut immune; early life; development ... See more keywords
Smoking affects gut immune system of patients with inflammatory bowel diseases by modulating metabolomic profiles and mucosal microbiota
Sign Up to like & getrecommendations! Published in 2025 at "Gut"
DOI: 10.1136/gutjnl-2025-334922
Abstract: Background The aetiology and pathogenesis of IBD are intricate, involving genetic and environmental factors. Notably, cigarette smoking has contrasting effects, being detrimental to Crohn’s disease (CD) and beneficial to UC. However, the mechanisms underlying these… read more here.
Keywords: immune system; mucosal microbiota; smoking affects; gut immune ... See more keywords
Gut-immune-brain interactions during neurodevelopment: from a brain-centric to a multisystem perspective
Sign Up to like & getrecommendations! Published in 2025 at "BMC Medicine"
DOI: 10.1186/s12916-025-04093-z
Abstract: Neurodevelopmental disorders (NDDs) and epileptic syndromes are complex neurological conditions linked by shared abnormal neurobiological processes. Existing therapies mostly target symptoms, rather than addressing the underlying causes of the disease, leaving a burden of unmet… read more here.
Keywords: brain; immune brain; gut immune; gut ... See more keywords
Functional and phenotypic analyses of porcine gut immune cells immunized by oral administration of F4ac+ nonenterotoxigenic Escherichia coli strains
Sign Up to like & getrecommendations! Published in 2018 at "Veterinarni Medicina"
DOI: 10.17221/5844-vetmed
Abstract: We attempted to determine whether or not F4ac+ nonenterotoxigenic Escherishia coli (non-ETEC) strains 2407 and 1466 tested as vaccine candidate strains are capable of priming porcine lymphocytes from jejunal lamina propria (JLP), ileal Peyer's patches… read more here.
Keywords: f4ac nonenterotoxigenic; coli; non etec; gut immune ... See more keywords
Dangers of the chronic stress response in the context of the microbiota-gut-immune-brain axis and mental health: a narrative review
Sign Up to like & getrecommendations! Published in 2024 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2024.1365871
Abstract: More than 20% of American adults live with a mental disorder, many of whom are treatment resistant or continue to experience symptoms. Other approaches are needed to improve mental health care, including prevention. The role… read more here.
Keywords: mental health; brain; microbiota gut; gut immune ... See more keywords
Immunomodulation by Gut Microbiome on Gastrointestinal Cancers: Focusing on Colorectal Cancer
Sign Up to like & getrecommendations! Published in 2022 at "Cancers"
DOI: 10.3390/cancers14092140
Abstract: Simple Summary A symbiotic relationship with the host gut microbiome influences the immune system’s development, functions, and activities. In the mucosa, the gut microbiome mediates several immune activities such as the induction of naïve T-cells… read more here.
Keywords: gut immune; cancer development; cancer; gut microbiome ... See more keywords
Dysbiosis Disrupts Gut Immune Homeostasis and Promotes Gastric Diseases
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms20102432
Abstract: Perturbation in the microbial population/colony index has harmful consequences on human health. Both biological and social factors influence the composition of the gut microbiota and also promote gastric diseases. Changes in the gut microbiota manifest… read more here.
Keywords: homeostasis promotes; gastric diseases; dysbiosis disrupts; immune homeostasis ... See more keywords