The synergistic link between sonic hedgehog signaling pathway and gut–lung axis: Its influential role toward chronic obstructive pulmonary disease progression
Sign Up to like & getrecommendations! Published in 2025 at "Developmental Dynamics"
DOI: 10.1002/dvdy.70006
Abstract: Sonic Hedgehog (SHH) is an evolutionarily conserved signaling pathway essential for embryonic development, tissue homeostasis, and tumorigenesis. Aberrant activation of the SHH pathway induces various types of cancer and different types of immune dysregulation. SHH… read more here.
Keywords: lung; shh; lung axis; gut lung ... See more keywords
Oral Multi-Enzymatic Manganese–Carbon Dots Alleviate Sepsis-Associated Lung Injury via the Gut–Lung Axis
Sign Up to like & getrecommendations! Published in 2025 at "ACS Nano"
DOI: 10.1021/acsnano.5c10625
Abstract: Sepsis-induced pulmonary injury represents a life-threatening global health challenge due to poorly defined pathological mechanisms. The gut-lung axis has been proven to be widely involved in sepsis-induced lung injury, yet effective interventions targeting gut microbiota… read more here.
Keywords: lung; lung injury; injury; gut lung ... See more keywords
Association of SARS-CoV-2 and Polypharmacy with Gut–Lung Axis: From Pathogenesis to Treatment
Sign Up to like & getrecommendations! Published in 2022 at "ACS Omega"
DOI: 10.1021/acsomega.2c02524
Abstract: SARS-CoV-2 is a novel infectious contagion leading to COVID-19 disease. The virus has affected the lives of millions of people across the globe with a high mortality rate. It predominantly affects the lung (respiratory system),… read more here.
Keywords: gut lung; polypharmacy; lung; lung axis ... See more keywords
Gut–lung crosstalk during critical illness
Sign Up to like & getrecommendations! Published in 2023 at "Current Opinion in Critical Care"
DOI: 10.1097/mcc.0000000000001015
Abstract: Purpose of review Study of organ crosstalk in critical illness has uncovered complex biological communication between different organ systems, but the role of microbiota in organ crosstalk has received limited attention. We highlight the emerging… read more here.
Keywords: gut; gut lung; lung; physiology ... See more keywords
The role of the lung microbiota and the gut–lung axis in respiratory infectious diseases
Sign Up to like & getrecommendations! Published in 2018 at "Cellular Microbiology"
DOI: 10.1111/cmi.12966
Abstract: The pulmonary microbial community, described only a few years ago, forms a discreet part of the human host microbiota. The airway microbiota has been found to be substantially altered in the context of numerous respiratory… read more here.
Keywords: gut; microbiota; role; gut lung ... See more keywords
Fungi affect gut-lung cross-talk
Sign Up to like & getrecommendations! Published in 2019 at "Science"
DOI: 10.1126/science.363.6423.138-d
Abstract: Immunology Fungal dysbiosis in the gut may occur after antibiotic treatment. This happens because specific microorganisms that support natural resistance are eliminated. In certain cases, fungal dysbiosis can promote allergic airway disease (AAD). Li et… read more here.
Keywords: cross talk; affect gut; gut lung; lung cross ... See more keywords
Mouse Subcutaneous BCG Vaccination and Mycobacterium tuberculosis Infection Alter the Lung and Gut Microbiota
Sign Up to like & getrecommendations! Published in 2022 at "Microbiology Spectrum"
DOI: 10.1128/spectrum.01693-21
Abstract: The microbial communities in gut and lung are important players that may modulate the immunity against tuberculosis or other infections as well as impact the vaccine efficacy. We discovered that vaccination through the subcutaneous route… read more here.
Keywords: tuberculosis; gut lung; infection; vaccination ... See more keywords
P63 Detection of viruses in the gut of children with bronchiolitis and viral induced wheeze – increasing our understanding of the gut-lung-axis
Sign Up to like & getrecommendations! Published in 2019 at "Thorax"
DOI: 10.1136/thorax-2019-btsabstracts2019.206
Abstract: Background Changes in the gut microbiome can affect the incidence of wheeze and bronchiolitis. There is little evidence in regard to the association between enteric viral populations and their potential effects on respiratory health. Methods… read more here.
Keywords: wheeze; viral induced; gut lung; induced wheeze ... See more keywords
Every breath you take: Impacts of environmental dust exposure on intestinal barrier function–from the gut-lung axis to COVID-19
Sign Up to like & getrecommendations! Published in 2021 at "American Journal of Physiology - Gastrointestinal and Liver Physiology"
DOI: 10.1152/ajpgi.00423.2020
Abstract: As countries continue to industrialize, major cities experience diminished air quality, while rural populations also experience poor air quality from sources such as agricultural operations. These exposures to environmental pollution from both rural and populated/industrialized… read more here.
Keywords: lung axis; covid; physiology; gut lung ... See more keywords
The Bidirectional Gut-Lung Axis in COPD.
Sign Up to like & getrecommendations! Published in 2023 at "American journal of respiratory and critical care medicine"
DOI: 10.1164/rccm.202206-1066tr
Abstract: Epidemiological studies indicate that chronic obstructive pulmonary disease (COPD) is associated with the incidence of changes in intestinal health. Cigarette smoking, as one of the major causes of COPD, can have an impact on the… read more here.
Keywords: lung axis; copd; bidirectional gut; gut lung ... See more keywords
The gut-lung axis and microbiome dysbiosis in non-tuberculous mycobacterial infections: immune mechanisms, clinical implications, and therapeutic frontiers
Sign Up to like & getrecommendations! Published in 2025 at "Gut Pathogens"
DOI: 10.1186/s13099-025-00718-z
Abstract: Non-tuberculous mycobacteria (NTM) are emerging pathogens of global concern, particularly in regions with declining tuberculosis rates. This review synthesizes current evidence on the epidemiology, immune pathogenesis, and microbiome interactions underlying NTM infections. The rising incidence… read more here.
Keywords: gut lung; lung axis; non tuberculous; microbiome dysbiosis ... See more keywords