Gut macrophages: key players in intestinal immunity and tissue physiology.
Sign Up to like & getrecommendations! Published in 2019 at "Current opinion in immunology"
DOI: 10.1016/j.coi.2019.11.011
Abstract: The mammalian gastrointestinal tract harbors a large reservoir of tissue macrophages, which, in concert with other immune cells, help to maintain a delicate balance between tolerance to commensal microbes and food antigens, and resistance to… read more here.
Keywords: key players; players intestinal; tissue; physiology ... See more keywords
Abstract 3442: FXR mediates macrophage intrinsic responses to suppress colon cancer progression
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-3442
Abstract: Bile acids (BAs) affect the intestinal environment by ensuring barrier integrity, regulating epithelium turnover, maintaining microbiota balance, and modulating the immune system. As a master regulator of BAs homeostasis and innate immunity, Farnesoid X Receptor… read more here.
Keywords: macrophage intrinsic; gut macrophages; colon cancer; fxr ... See more keywords