The Potential of the Gut Microbiome to Reshape the Cancer Therapy Paradigm: A Review.
Sign Up to like & getrecommendations! Published in 2022 at "JAMA oncology"
DOI: 10.1001/jamaoncol.2022.0494
Abstract: Importance The gut microbiome, home to the vast kingdom of diverse commensal bacteria and other microorganisms residing within the gut, was once thought to only have roles primarily centered on digestive functions. However, recent advances… read more here.
Keywords: cancer therapy; cancer; gut microbiome;
Interplay of Metabolome and Gut Microbiome in Individuals With Major Depressive Disorder vs Control Individuals.
Sign Up to like & getrecommendations! Published in 2023 at "JAMA psychiatry"
DOI: 10.1001/jamapsychiatry.2023.0685
Abstract: Importance Metabolomics reflect the net effect of genetic and environmental influences and thus provide a comprehensive approach to evaluating the pathogenesis of complex diseases, such as depression. Objective To identify the metabolic signatures of major… read more here.
Keywords: control individuals; study; gut microbiome;
Integrative analysis of gut microbiome and host transcriptomes reveals associations between treatment outcomes and immunotherapy-induced colitis.
Sign Up to like & getrecommendations! Published in 2021 at "Molecular oncology"
DOI: 10.1002/1878-0261.13062
Abstract: Immune checkpoint inhibitors (ICIs) are widely used to treat various malignancies. Although the gut microbiome is known to influence the efficacy of ICIs on epithelial tumors, the functional interactions between gut taxa and colonic mucosa remain… read more here.
Keywords: integrative analysis; host transcriptomes; gut microbiome; microbiome ... See more keywords
Dietary interventions, the gut microbiome, and aggressive behavior: Review of research evidence and potential next steps.
Sign Up to like & getrecommendations! Published in 2022 at "Aggressive behavior"
DOI: 10.1002/ab.22050
Abstract: Research in biosocial criminology and other related disciplines has established links between nutrition and aggressive behavior. In addition to observational studies, randomized trials of nutritional supplements like vitamins, omega-3 fatty acids, and folic acid provide… read more here.
Keywords: behavior; dietary interventions; gut microbiome; criminology ... See more keywords
Bioengineered 3D Tissue Model of Intestine Epithelium with Oxygen Gradients to Sustain Human Gut Microbiome
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202200447
Abstract: The human gut microbiome is crucial to hosting physiology and health. Therefore, stable in vitro coculture of primary human intestinal cells with a microbiome community is essential for understanding intestinal disease progression and revealing novel… read more here.
Keywords: epithelium; oxygen gradients; oxygen; gut microbiome ... See more keywords
Probiotic‐Inspired Nanomedicine Restores Intestinal Homeostasis in Colitis by Regulating Redox Balance, Immune Responses, and the Gut Microbiome
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Materials"
DOI: 10.1002/adma.202207890
Abstract: Microbiota‐based therapeutics offer innovative strategies to treat inflammatory bowel diseases (IBDs). However, the poor clinical outcome so far and the limited flexibility of the bacterial approach call for improvement. Inspired by the health benefits of… read more here.
Keywords: colitis; redox balance; gut microbiome; balance immune ... See more keywords
The Gut Microbiome Dynamically Associates with Host Glucose Metabolism throughout Pregnancy: Longitudinal Findings from a Matched Case‐Control Study of Gestational Diabetes Mellitus
Sign Up to like & getrecommendations! Published in 2023 at "Advanced Science"
DOI: 10.1002/advs.202205289
Abstract: Though gut microbiome disturbance may be involved in the etiology of gestational diabetes mellitus (GDM), data on the gut microbiome's dynamic change during pregnancy and associations with gestational glucose metabolism are still inadequate. In this… read more here.
Keywords: gut microbiome; glucose metabolism; gestational diabetes; pregnancy ... See more keywords
Age‐related changes in the marmoset gut microbiome
Sign Up to like & getrecommendations! Published in 2019 at "American Journal of Primatology"
DOI: 10.1002/ajp.22960
Abstract: The gut microbiome is known to play a significant role in human health but its role in aging remains unclear. The objective of this study was to compare the gut microbiome composition between young adult… read more here.
Keywords: young adult; compared young; marmosets significantly; geriatric marmosets ... See more keywords
Primate microbiomes over time: Longitudinal answers to standing questions in microbiome research
Sign Up to like & getrecommendations! Published in 2019 at "American Journal of Primatology"
DOI: 10.1002/ajp.22970
Abstract: To date, most insights into the processes shaping vertebrate gut microbiomes have emerged from studies with cross‐sectional designs. While this approach has been valuable, emerging time series analyses on vertebrate gut microbiomes show that gut… read more here.
Keywords: microbiome research; primate microbiomes; time; microbiomes time ... See more keywords
Gut microbiome composition of wild western lowland gorillas is associated with individual age and sex factors.
Sign Up to like & getrecommendations! Published in 2019 at "American journal of physical anthropology"
DOI: 10.1002/ajpa.23842
Abstract: OBJECTIVES Environmental and ecological factors, such as geographic range, anthropogenic pressure, group identity, and feeding behavior are known to influence the gastrointestinal microbiomes of great apes. However, the influence of individual host traits such as… read more here.
Keywords: gorilla; age sex; sex; composition ... See more keywords
Gut microbiome influences on anastomotic leak and recurrence rates following colorectal cancer surgery
Sign Up to like & getrecommendations! Published in 2018 at "British Journal of Surgery"
DOI: 10.1002/bjs.10760
Abstract: The pathogenesis of colorectal cancer recurrence after a curative resection remains poorly understood. A yet‐to‐be accounted for variable is the composition and function of the microbiome adjacent to the tumour and its influence on the… read more here.
Keywords: recurrence; colorectal cancer; surgery gut; gut microbiome ... See more keywords