The Gut Resistome Atlas in Preterm Infants Enables Prediction of Necrotizing Enterocolitis Onset
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Science"
DOI: 10.1002/advs.202505154
Abstract: The accelerating threat from antimicrobial resistance (AMR) has become a global health issue. The properties of AMR in the gut microbiome of preterm infants and its clinical relevance with necrotizing enterocolitis (NEC) remain unknown. In‐depth… read more here.
Keywords: resistome atlas; necrotizing enterocolitis; preterm infants; nec onset ... See more keywords
Breastfeeding and early Bifidobacterium-driven microbial colonization shape the infant gut resistome
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DOI: 10.1038/s41467-025-61154-w
Abstract: The assembly of the gut resistome in early life is key to infant health. Specific perinatal factors such as cesarean section (C-section), antibiotic exposure and lack of breastfeeding practices are detrimental to proper microbial development… read more here.
Keywords: life; bifidobacterium; gut resistome; breastfeeding ... See more keywords
Temporal dynamics and microbial interactions shaping the gut resistome in early infancy
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DOI: 10.1038/s41467-025-63401-6
Abstract: Despite the critical role of the gut resistome in spreading of antimicrobial resistance (AMR), strategies to reduce the abundance of antibiotic resistance genes (ARGs) during microbiota development in infancy remain underexplored. Using longitudinal quantitative metagenomic… read more here.
Keywords: aromatic lactic; resistance; gut resistome; microbial interactions ... See more keywords
High-fat and low-fiber diet elevates the gut resistome: a comparative metagenomic study
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DOI: 10.1038/s41522-025-00799-3
Abstract: Antimicrobial resistance (AMR) is a global health challenge. The gut microbiome, a major reservoir for AMR, is influenced by dietary habits. However, the specific impact of dietary patterns on gut resistome remains poorly understood. This… read more here.
Keywords: high fiber; gut resistome; fiber; low fiber ... See more keywords
The association between early life antibiotic exposure and the gut resistome of young children: a systematic review
Sign Up to like & getrecommendations! Published in 2022 at "Gut Microbes"
DOI: 10.1080/19490976.2022.2120743
Abstract: ABSTRACT Antimicrobial resistance is a growing public health burden, but little is known about the effects of antibiotic exposure on the gut resistome. As childhood (0–5 years) represents a sensitive window of microbiome development and… read more here.
Keywords: antibiotic exposure; gut resistome; review; resistance ... See more keywords
Influence of age, socioeconomic status, and location on the infant gut resistome across populations
Sign Up to like & getrecommendations! Published in 2024 at "Gut Microbes"
DOI: 10.1080/19490976.2023.2297837
Abstract: ABSTRACT Antibiotic resistance is a growing global concern, with many ecological niches showing a high abundance of antibiotic resistance genes (ARGs), including the human gut. With increasing indications of ARGs in infants, this study aims… read more here.
Keywords: abundance; gut; infant gut; socioeconomic status ... See more keywords
Double-edged sword: impact of fecal microbiome transplants on the gut resistome
Sign Up to like & getrecommendations! Published in 2022 at "Current Opinion in Gastroenterology"
DOI: 10.1097/mog.0000000000000894
Abstract: Purpose of review Fecal microbiome transplants (FMT) show promise in treating various diseases, such as Clostridioides difficile infections. FMT have also demonstrated the capacity to modulate the collection of antibiotic resistance genes (ARGs), termed the… read more here.
Keywords: gut resistome; fecal microbiome; double edged; microbiome transplants ... See more keywords
Food substances alter gut resistome: Mechanisms, health impacts, and food components
Sign Up to like & getrecommendations! Published in 2025 at "Comprehensive Reviews in Food Science and Food Safety"
DOI: 10.1111/1541-4337.70143
Abstract: Abstract Antibiotics are effective in treating bacterial infections, but their widespread use has spurred antibiotic resistance, which is linked closely with human disease. While dietary components are known to influence the gut microbiome, specific effects… read more here.
Keywords: food; resistance; alter gut; food substances ... See more keywords
Temporal development and potential interactions between the gut microbiome and resistome in early childhood
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DOI: 10.1128/spectrum.03177-23
Abstract: ABSTRACT Antimicrobial resistance-associated infections have become a major threat to global health. The gut microbiome serves as a major reservoir of bacteria with antibiotic resistance genes; whereas, the temporal development of gut resistome during early… read more here.
Keywords: microbiome resistome; early childhood; gut microbiome; antibiotic exposure ... See more keywords
Ribaxamase, an Orally Administered β-Lactamase, Diminishes Changes to Acquired Antimicrobial Resistance of the Gut Resistome in Patients Treated with Ceftriaxone
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DOI: 10.2147/idr.s260258
Abstract: Introduction Intravenous (IV) β-lactam antibiotics, excreted through bile into the gastrointestinal (GI) tract, may disrupt the gut microbiome by eliminating the colonization resistance from beneficial bacteria. This increases the risk for Clostridium difficile infection (CDI)… read more here.
Keywords: lactamase; resistance; gut resistome; antimicrobial resistance ... See more keywords
Dose-dependent impact of enrofloxacin on broiler chicken gut resistome is mitigated by synbiotic application
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2022.869538
Abstract: Fluoroquinolone agents are considered critical for human medicine by the World Health Organization (WHO). However, they are often used for the treatment of avian colibacillosis in poultry production, creating considerable concern regarding the potential spread… read more here.
Keywords: application; broiler; dose dependent; gut resistome ... See more keywords