Synthesis of novel guttiferone E and xanthochymol derivatives with cytotoxicities by inducing cell apoptosis and arresting the cell cycle phase.
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DOI: 10.1016/j.ejmech.2018.11.046
Abstract: The mixture of GX (guttiferone E and xanthochymol), an inseparable polycyclic polyprenylated acylphloroglucinol (PPAP), showed moderate cytotoxic activities. The chemical transformation of GX yielded three different types of PPAPs (1, 2, and 3/4). A series… read more here.
Keywords: cell line; cell cycle; cycle phase; guttiferone xanthochymol ... See more keywords