Ornithine decarboxylase or gamma-glutamylcysteine synthetase overexpression protects Leishmania (Vianna) guyanensis against antimony.
Sign Up to like & getrecommendations! Published in 2017 at "Experimental parasitology"
DOI: 10.1016/j.exppara.2017.02.001
Abstract: Trypanosomatids present a unique mechanism for detoxification of peroxides that is dependent on trypanothione (bisglutathionylspermidine). Ornithine decarboxylase (ODC) and γ-glutamylcysteine synthetase (GSH1) produce molecules that are direct precursors of trypanothione. In this study, Leishmania guyanensis… read more here.
Keywords: gsh1; ornithine decarboxylase; glutamylcysteine synthetase; guyanensis ... See more keywords
Treating leishmaniasis in Amazonia, part 2: Multi-target evaluation of widely used plants to understand medicinal practices.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of ethnopharmacology"
DOI: 10.1016/j.jep.2022.115054
Abstract: ETHNOPHARMACOLOGICAL RELEVANCE Leishmaniasis are widely distributed among tropical and subtropical countries, and remains a crucial health issue in Amazonia. Indigenous groups across Amazonia have developed abundant knowledge about medicinal plants related to this pathology. AIM… read more here.
Keywords: guyanensis; evaluation; wound healing; activity ... See more keywords
Structurally Diverse Diterpenoids from Sandwithia guyanensis.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of natural products"
DOI: 10.1021/acs.jnatprod.7b01025
Abstract: Bioassay-guided fractionation of an EtOAc extract of the trunk bark of Sandwithia guyanensis, using a chikungunya virus (CHIKV)-cell-based assay, afforded 17 new diterpenoids 1-17 and the known jatrointelones A and C (18 and 19). The… read more here.
Keywords: diterpenoids sandwithia; diverse diterpenoids; sandwithia guyanensis; guyanensis ... See more keywords
Multiple evolutionary lineages for the main vector of Leishmania guyanensis, Lutzomyia umbratilis (Diptera: Psychodidae), in the Brazilian Amazon
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-93072-4
Abstract: Lutzomyia umbratilis is the main vector of Leishmania guyanensis in the Brazilian Amazon and in neighboring countries. Previous biological and molecular investigations have revealed significant differences between L. umbratilis populations from the central Brazilian Amazon… read more here.
Keywords: vector; brazilian amazon; amazon; river ... See more keywords
Leishmania (Viannia) guyanensis in tegumentary leishmaniasis
Sign Up to like & getrecommendations! Published in 2018 at "Pathogens and Disease"
DOI: 10.1093/femspd/fty025
Abstract: Abstract Leishmania (Viannia) guyanensis is a causal agent of American tegumentary leishmaniasis (ATL). This protozoan has been poorly investigated; however, it can cause different clinical forms of ATL, ranging from a single cutaneous lesion to… read more here.
Keywords: tegumentary leishmaniasis; guyanensis; leishmania viannia; viannia guyanensis ... See more keywords
Leishmania guyanensis M4147 as a new LRV1-bearing model parasite: Phosphatidate phosphatase 2-like protein controls cell cycle progression and intracellular lipid content
Sign Up to like & getrecommendations! Published in 2022 at "PLoS Neglected Tropical Diseases"
DOI: 10.1371/journal.pntd.0010510
Abstract: Leishmaniasis is a parasitic vector-borne disease caused by the protistan flagellates of the genus Leishmania. Leishmania (Viannia) guyanensis is one of the most common causative agents of the American tegumentary leishmaniasis. It has previously been… read more here.
Keywords: phosphatase like; guyanensis m4147; guyanensis; cell cycle ... See more keywords
Crecimiento de Mytella guyanensis (Bivalvia: Mytilidae) en balsas flotantes
Sign Up to like & getrecommendations! Published in 2017 at "Revista De Biologia Tropical"
DOI: 10.15517/rbt.v46i6.29630
Abstract: Se estudio el crecimiento del mitilido Mycella guyanensis en una estructura flotante en Isla de Chira, Golfo de Nicoya, Costa Rica. Se recolecto semilla natural con colectores que fueron colocados en la estructura suspendida por… read more here.
Keywords: mytella guyanensis; guyanensis bivalvia; crecimiento mytella; mytilidae balsas ... See more keywords
Identification of Antimicrobial Compounds from Sandwithia guyanensis-Associated Endophyte Using Molecular Network Approach
Sign Up to like & getrecommendations! Published in 2019 at "Plants"
DOI: 10.3390/plants9010047
Abstract: The emergence of multidrug resistant bacterial pathogens and the increase of antimicrobial resistance constitutes a major health challenge, leading to intense research efforts being focused on the discovery of novel antimicrobial compounds. In this study,… read more here.
Keywords: antimicrobial compounds; molecular network; sandwithia guyanensis; using molecular ... See more keywords