Articles with "gvhd suppressor" as a keyword



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S100A9 up-regulated by IFNGR signaling blockade functions as a novel GvHD suppressor without compromising GvL in mice.

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Published in 2022 at "Blood"

DOI: 10.1182/blood.2021012687

Abstract: Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is a curative treatment for both malignant and nonmalignant hematologic disorders. However, graft-versus-host disease (GvHD) and malignant relapse limit its therapeutic success. We previously demonstrated that blockade of interferon-gamma… read more here.

Keywords: ifngr signaling; s100a9; gvhd; gvhd suppressor ... See more keywords