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GW28-e0577 Trimethylamine-N-oxide induces the osteogenic responses of human aortic valve interstitisl cells through the endoplasmic reticulum-mitochondrial stress pathways

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Published in 2017 at "Journal of the American College of Cardiology"

DOI: 10.1016/j.jacc.2017.07.061

Abstract: The recent studies show that the choline-derived metabolite trimethylamine N-oxide (TMAO) levels are associated with the development of cardiovascular diseases. TMAO causes cell inflammation and endoplasmic reticulum stress. Inflammatory responses and endoplasmic reticulum stress are involved… read more here.

Keywords: endoplasmic reticulum; reticulum; trimethylamine oxide; stress ... See more keywords