Comprehensive evaluation of disease- and trait-specific enrichment for eight functional elements among GWAS-identified variants
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DOI: 10.1007/s00439-017-1815-6
Abstract: Genome-wide association study (GWAS)-identified variants are enriched for functional elements. However, we have limited knowledge of how functional enrichment may differ by disease/trait and tissue type. We tested a broad set of eight functional elements… read more here.
Keywords: trait; functional elements; disease trait; eight functional ... See more keywords
Evaluation of GWAS-Identified Genetic Variants for Gastric Cancer Survival
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DOI: 10.1016/j.ebiom.2018.06.028
Abstract: Backgrounds Genome-wide association studies (GWASs) have identified several gastric cancer (GC) susceptibility loci in Asians, but their effects on disease outcome are still unknown. This study aimed to investigate whether these GWAS-identified genetic variants could… read more here.
Keywords: identified genetic; gastric cancer; genetic variants; gwas identified ... See more keywords
Association of Genome-Wide Association Study (GWAS) Identified SNPs and Risk of Breast Cancer in an Indian Population
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DOI: 10.1038/srep40963
Abstract: To date, no studies have investigated the association of the GWAS-identified SNPs with BC risk in Indian population. We investigated the association of 30 previously reported and replicated BC susceptibility SNPs in 1,204 cases and… read more here.
Keywords: risk; indian population; snps; association ... See more keywords