Treatment for Gulf War Illness (GWI) with KPAX002 (methylphenidate hydrochloride + GWI nutrient formula) in subjects meeting the Kansas case definition: A prospective, open-label trial (revision 2).
Sign Up to like & getrecommendations! Published in 2019 at "Journal of psychiatric research"
DOI: 10.1016/j.jpsychires.2019.08.003
Abstract: This study tested the safety, tolerability, and efficacy of KPAX002-a combination of methylphenidate hydrochloride plus a micronutrient formula designed to support mitochondrial function-as a treatment for Gulf War Illness (GWI). This open-label trial enrolled 17… read more here.
Keywords: gulf war; trial; war illness; methylphenidate hydrochloride ... See more keywords
Gulf War illness in the Gulf War Era Cohort and Biorepository: The Kansas and centers for disease control definitions.
Sign Up to like & getrecommendations! Published in 2021 at "Life sciences"
DOI: 10.1016/j.lfs.2021.119454
Abstract: AIMS This study characterizes Gulf War Illness (GWI) among U.S. veterans who participated in the Gulf War Era Cohort and Biorepository (GWECB). MAIN METHODS Mailed questionnaires were collected between 2014 and 2016. Self-reported GWI symptoms,… read more here.
Keywords: status; gulf war; war era; war ... See more keywords
Melatonin improves brain function in a model of chronic Gulf War Illness with modulation of oxidative stress, NLRP3 inflammasomes, and BDNF-ERK-CREB pathway in the hippocampus
Sign Up to like & getrecommendations! Published in 2021 at "Redox Biology"
DOI: 10.1016/j.redox.2021.101973
Abstract: Persistent cognitive and mood dysfunction is the primary CNS symptom in veterans afflicted with Gulf War Illness (GWI). This study investigated the efficacy of melatonin (MEL) for improving cognitive and mood function with antioxidant, antiinflammatory,… read more here.
Keywords: hippocampus; mel; model chronic; cognitive mood ... See more keywords
Preserved left ventricular ejection fraction with abnormal myocardial work in sepsis
Sign Up to like & getrecommendations! Published in 2024 at "European Heart Journal"
DOI: 10.1093/eurheartj/ehae666.1729
Abstract: Sepsis is a life-threatening condition associated with a dysregulated response to infection, leading to an increased risk of multi-organ dysfunction and death. Left ventricular (LV) dysfunction has been reported in up to 60% of patients… read more here.
Keywords: gwi; work; left ventricular; ejection fraction ... See more keywords
Neurovascular Coupling Response to Cognitive Challenges in Gulf War Veterans
Sign Up to like & getrecommendations! Published in 2025 at "Physiology"
DOI: 10.1152/physiol.2025.40.s1.0364
Abstract: Gulf War Illness (GWI) is a multi-symptom disease in Gulf War Veterans associated with cognitive complaints, fatigue, and muscular pain. Neurovascular coupling (NVC) reflects the increase in blood flow in response to elevations in neural… read more here.
Keywords: gwi; physiology; bsl; gwi gwi ... See more keywords
The impact of post-traumatic stress on quality of life and fatigue in women with Gulf War Illness
Sign Up to like & getrecommendations! Published in 2022 at "BMC Psychology"
DOI: 10.1186/s40359-022-00752-5
Abstract: Background Gulf War Illness (GWI) is a chronic, multi-symptomatic disorder characterized by fatigue, muscle pain, cognitive problems, insomnia, rashes, and gastrointestinal issues affecting an estimated 30% of the ~ 750,000 returning military Veterans of the 1990–1991 Persian Gulf War. Female… read more here.
Keywords: gulf war; quality life; war; gwi ... See more keywords
FDA-approved cannabidiol [Epidiolex®] alleviates Gulf War Illness-linked cognitive and mood dysfunction, hyperalgesia, neuroinflammatory signaling, and declined neurogenesis
Sign Up to like & getrecommendations! Published in 2024 at "Military Medical Research"
DOI: 10.1186/s40779-024-00563-2
Abstract: Chronic Gulf War Illness (GWI) is characterized by cognitive and mood impairments, as well as persistent neuroinflammation and oxidative stress. This study aimed to investigate the efficacy of Epidiolex®, a Food and Drug Administration (FDA)-approved… read more here.
Keywords: gwi; gulf war; cognitive mood; war illness ... See more keywords
Brain-Specific Increase in Leukotriene Signaling Accompanies Chronic Neuroinflammation and Cognitive Impairment in a Model of Gulf War Illness
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.853000
Abstract: Persistent cognitive impairment is a primary central nervous system-related symptom in veterans afflicted with chronic Gulf War Illness (GWI). Previous studies in a rat model have revealed that cognitive dysfunction in chronic GWI is associated… read more here.
Keywords: neuroinflammation; gulf war; brain; cognitive impairment ... See more keywords
Modified tarsorrhaphy versus gold weight implant technique for paralytic lagophthalmos treatment in patients with leprosy: One-year observation of a randomized controlled trial study
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Medicine"
DOI: 10.3389/fmed.2022.941082
Abstract: Trial design This study was a multicenter, Prospective Randomized Open-label Blinded-Endpoint (PROBE) clinical trial, parallel-group study conducted in Indonesia (three sites). Methods The aim of this study was to compare the effectivity and efficiency of… read more here.
Keywords: paralytic lagophthalmos; trial; group; gwi ... See more keywords
A Double-Humanized Mouse Model for Studying Host Gut Microbiome–Immune Interactions in Gulf War Illness
Sign Up to like & getrecommendations! Published in 2024 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms25116093
Abstract: Unraveling the multisymptomatic Gulf War Illness (GWI) pathology and finding an effective cure have eluded researchers for decades. The chronic symptom persistence and limitations for studying the etiologies in mouse models that differ significantly from… read more here.
Keywords: gwi; gulf war; pathology; model ... See more keywords