GYF-21, an epoxide 2‑(2‑phenethyl)‑chromone derivative, suppresses dysfunction of B cells mainly via inhibiting BAFF activated signaling pathways.
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DOI: 10.1016/j.intimp.2018.12.048
Abstract: Activated B cells targeted to autoantigens proliferate and differentiate into antibody-secreting cells. Overproduced autoantibodies will give rise to autoimmune diseases. In this study, we investigated the inhibitory effects of GYF-21, an epoxide 2‑(2‑phenethyl)‑chromone derivative extracted… read more here.
Keywords: epoxide phenethyl; phenethyl chromone; autoimmune diseases; chromone derivative ... See more keywords