Prognostic and Clinicopathological Significance of ARID1A in Endometrium‐Related Gynecological Cancers: A Meta‐Analysis
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.26109
Abstract: The tumor suppressor gene, AT Rich Interactive Domain 1A (ARID1A) mutation has been reported in a variety of cancers, especially the endometrium‐related gynecological cancers, including the ovarian clear cell carcinoma, ovarian endometrioid carcinoma, and uterine… read more here.
Keywords: gynecological cancers; related gynecological; endometrium related; arid1a endometrium ... See more keywords
Management of endometrial, ovarian and cervical cancer in the elderly: current approach to a challenging condition
Sign Up to like & getrecommendations! Published in 2018 at "Archives of Gynecology and Obstetrics"
DOI: 10.1007/s00404-018-5006-z
Abstract: AbstractPurposeGynaecological cancer management in older people represents a current challenge. Therefore, in the present paper, we aimed to gather all the evidence reported in the literature concerning gynecological cancers in the elderly, illustrating the state… read more here.
Keywords: management endometrial; gynecological cancers; endometrial ovarian; cervical cancer ... See more keywords
Economic Burden of Gynecological Cancers in Iran.
Sign Up to like & getrecommendations! Published in 2021 at "Value in health regional issues"
DOI: 10.1016/j.vhri.2021.02.005
Abstract: BACKGROUND Gynecological cancers (GCs) are an important cause of morbidity and mortality among women worldwide. The incidence of cancer is increasing in Iran, and according to statistics, it has become the most important cause of… read more here.
Keywords: gynecological cancers; economic burden; cancers iran; gcs ... See more keywords
ATARI trial: ATR inhibitor in combination with olaparib in gynecological cancers with ARID1A loss or no loss (ENGOT/GYN1/NCRI)
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Gynecological Cancer"
DOI: 10.1136/ijgc-2021-002973
Abstract: Background ARID1A (AT-rich interactive domain containing protein 1A) loss-of-function mutations have been reported in gynecological cancers, including rarer subtypes such as clear cell carcinoma. Preclinical studies indicate that ARID1A mutant cancers display sensitivity to ATR… read more here.
Keywords: combination; arid1a loss; trial; gynecological cancers ... See more keywords
Ubiquitin levels: the next target against gynecological cancers?
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Clinical Investigation"
DOI: 10.1172/jci98262
Abstract: Ubiquitylation is a tightly regulated process that is essential for appropriate cell survival and function, and the ubiquitin pathway has shown promise as a therapeutic target for several forms of cancer. In this issue of… read more here.
Keywords: levels next; gynecological cancers; target; ubiquitin levels ... See more keywords
Assessing the quality of patient-reported outcome measurements for gynecological cancers: a systematic review.
Sign Up to like & getrecommendations! Published in 2023 at "Future oncology"
DOI: 10.2217/fon-2022-0111
Abstract: Purpose: To provide perspective on patient-reported outcome measurement (PROM) instruments to adopt in patients diagnosed with gynecological cancers. Methods: A systematic search was conducted to identify PROMs developed for or applied in gynecological cancer populations. PROMs… read more here.
Keywords: quality; gynecological cancers; patient reported; gynecological cancer ... See more keywords
A Comprehensive Overview of circRNAs: Emerging Biomarkers and Potential Therapeutics in Gynecological Cancers
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2021.709512
Abstract: Circular RNA (circRNA) is a highly conserved, stable and abundant non-coding RNA (ncRNA). Also, some circRNAs play an essential part in the progression of human cancers. CircRNA is different from traditional linear RNA. CircRNA has… read more here.
Keywords: gynecological tumors; overview circrnas; gynecological cancers; rna ... See more keywords
Design of Peptide-Based Nanovaccines Targeting Leading Antigens From Gynecological Cancers to Induce HLA-A2.1 Restricted CD8+ T Cell Responses
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2018.02968
Abstract: Gynecological cancers are a leading cause of mortality in women. CD8+ T cell immunity largely correlates with enhanced survival, whereas inflammation is associated with poor prognosis. Previous studies have shown polystyrene nanoparticles (PSNPs) are biocompatible,… read more here.
Keywords: cd8 cell; cell responses; gynecological cancers; vaccine ... See more keywords
Immune-Onco-Microbiome: A New Revolution for Gynecological Cancers
Sign Up to like & getrecommendations! Published in 2023 at "Biomedicines"
DOI: 10.3390/biomedicines11030782
Abstract: Despite significant advances in understanding the pathogenetic mechanisms underlying gynaecological cancers, these cancers still remain widespread. Recent research points to a possible link between microbiota and cancer, and the most recent attention is focusing on… read more here.
Keywords: new revolution; gynecological cancers; revolution gynecological; onco microbiome ... See more keywords
The Expression, Functions and Mechanisms of Circular RNAs in Gynecological Cancers
Sign Up to like & getrecommendations! Published in 2020 at "Cancers"
DOI: 10.3390/cancers12061472
Abstract: Circular RNAs (circRNAs) are covalently closed, endogenous non-coding RNAs and certain circRNAs are linked to human tumors. Owing to their circular form, circRNAs are protected from degradation by exonucleases, and therefore, they are more stable… read more here.
Keywords: expression functions; circular rnas; functions mechanisms; gynecological cancers ... See more keywords
Hormonal Therapy for Gynecological Cancers: How Far Has Science Progressed toward Clinical Applications?
Sign Up to like & getrecommendations! Published in 2022 at "Cancers"
DOI: 10.3390/cancers14030759
Abstract: Simple Summary The most common therapies for severe and recurrent gynecological cancers are hormone therapy and chemotherapy, and responsiveness to therapy is a key component in prognosis and survivability. Hormone therapy has recently been demonstrated… read more here.
Keywords: hormone; hormonal therapy; gynecological cancers; therapy ... See more keywords