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   Articles with "gynostemma pentaphyllum" as a keyword



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New dammarane-type glycosides from Gynostemma pentaphyllum and their lipid-lowering activity.

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recommendations! Published in 2021 at "Bioorganic chemistry"

DOI: 10.1016/j.bioorg.2021.104843

Abstract: Gynostemma pentaphyllum (Thunb.) Makino has a long history as food and diary supplement in China. At present, there are some products for hyperlipidemia in the market, including G. pentaphyllum tea, healthy wine and healthy food.… read more here.

Keywords: type glycosides; dammarane type; gynostemma pentaphyllum; pentaphyllum ... See more keywords
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Anti-diabetic activity evaluation of a polysaccharide extracted from Gynostemma pentaphyllum.

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recommendations! Published in 2019 at "International journal of biological macromolecules"

DOI: 10.1016/j.ijbiomac.2018.12.231

Abstract: In current study, a polysaccharide (GPP) was successfully extracted from Gynostemma pentaphyllum herb. Monosaccharide composition of GPP was rhamnose, arabinose, galactose, glucose, xylose, mannose, galacturonic acid and glucuronic acid in a molar ratio of 4.11:… read more here.

Keywords: gpp; extracted gynostemma; gynostemma pentaphyllum; polysaccharide ... See more keywords
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Anti‐atherosclerotic effect of Fermentum Rubrum and Gynostemma pentaphyllum mixture in high‐fat emulsion‐ and vitamin D3‐induced atherosclerotic rats

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recommendations! Published in 2018 at "Journal of the Chinese Medical Association"

DOI: 10.1016/j.jcma.2017.08.018

Abstract: Background: The mixture of Hongqu and gypenosides (HG) is composed of Fermentum Rubrum (Hongqu, in Chinese) and total saponins of Gynostemma pentaphyllum (Thunb.) Makino (Jiaogulan, in Chinese) in a 3.6:1 weight ratio. Both Hongqu and… read more here.

Keywords: hongqu; fermentum rubrum; atherosclerotic effect; gynostemma pentaphyllum ... See more keywords
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Chemical Characterization and Atherosclerosis Alleviation Effects of Gypenosides from Gynostemma pentaphyllum through Ameliorating Endothelial Dysfunction via the PCSK9/LOX-1 Pathway.

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recommendations! Published in 2022 at "Journal of agricultural and food chemistry"

DOI: 10.1021/acs.jafc.2c02681

Abstract: Dietary saponins have the potential to ameliorate atherosclerosis (AS). Gypenosides of Gynostemma pentaphyllum (GPs) have been used as functional foods to exhibit antiatherosclerotic activity. The present study aimed to explore the protective effect, underlying mechanism… read more here.

Keywords: gypenosides gynostemma; pcsk9; pcsk9 lox; gynostemma pentaphyllum ... See more keywords
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Dammarane-Type Saponins from Gynostemma pentaphyllum prevent hypoxia-induced neural injury through activation of ERK, Akt and CREB pathways.

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recommendations! Published in 2019 at "Journal of agricultural and food chemistry"

DOI: 10.1021/acs.jafc.9b06659

Abstract: Gynostemma pentaphyllum possesses the neuroprotective bioactivity. However, the effect of gypenosides on the hypoxia-induced neural damage remains obscure. In this study, Gyp, the active fraction extracted from G. pentaphyllum, and its bioactive compounds as well… read more here.

Keywords: akt creb; erk akt; gynostemma pentaphyllum; injury ... See more keywords

Gypenoside biotransformation into ginsenoside F2 by endophytic Aspergillus niger from Gynostemma pentaphyllum.

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recommendations! Published in 2023 at "Natural product research"

DOI: 10.1080/14786419.2023.2209823

Abstract: Ginsenoside F2 is a protopanaxadiol saponin compound with various biological activities, including antioxidant, anti-inflammatory, and anticancer properties. Ginsenoside F2 can be found in ginseng, but in low quantities. Therefore, ginsenoside F2 production predominantly relies on… read more here.

Keywords: gypenoside biotransformation; ginsenoside; biotransformation; aspergillus niger ... See more keywords
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Gynostemma pentaphyllum polysaccharides ameliorate non-alcoholic steatohepatitis in mice associated with gut microbiota and the TLR2/NLRP3 pathway

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recommendations! Published in 2022 at "Frontiers in Endocrinology"

DOI: 10.3389/fendo.2022.885039

Abstract: Recent studies have revealed the pivotal role of gut microbiota in the progress of liver diseases including non-alcoholic steatohepatitis (NASH). Many natural herbs, such as Gynostemma pentaphyllum (GP), have been extensively applied in the prevention… read more here.

Keywords: alcoholic steatohepatitis; non alcoholic; microbiota; gut microbiota ... See more keywords
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Effect of Polysaccharide Extracted From Gynostemma Pentaphyllum on the Body Weight and Gut Microbiota of Mice

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recommendations! Published in 2022 at "Frontiers in Nutrition"

DOI: 10.3389/fnut.2022.916425

Abstract: Researchers have investigated the role of polysaccharides in disease treatment via gut microbiota regulation but ignore their function in disease prevention and physique enhancement. In this work, a Gynostemma pentaphyllum polysaccharide (GPP) was tested by… read more here.

Keywords: body weight; gynostemma pentaphyllum; microbiota; gut microbiota ... See more keywords
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Gynostemma pentaphyllum for dyslipidemia: A systematic review of randomized controlled trials

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recommendations! Published in 2022 at "Frontiers in Pharmacology"

DOI: 10.3389/fphar.2022.917521

Abstract: Objective: To evaluate the lipid-lowering effect and safety of Gynostemma pentaphyllum (GP) used alone or as adjunctive therapy for dyslipidemia. Methods: Eight databases and three clinical trial registries were searched until January 2022. Randomized controlled… read more here.

Keywords: lowering agents; mmol; gynostemma pentaphyllum; lipid lowering ... See more keywords

Genome-Wide Identification of R2R3-MYB Transcription Factors: Discovery of a “Dual-Function” Regulator of Gypenoside and Flavonol Biosynthesis in Gynostemma pentaphyllum

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recommendations! Published in 2022 at "Frontiers in Plant Science"

DOI: 10.3389/fpls.2021.796248

Abstract: The R2R3-MYB gene family participates in several plant physiological processes, especially the regulation of the biosynthesis of secondary metabolites. However, little is known about the functions of R2R3-MYB genes in Gynostemma pentaphyllum (G. pentaphyllum), a… read more here.

Keywords: biosynthesis; r2r3 myb; gypenoside flavonol; gynostemma pentaphyllum ... See more keywords
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Comparative Transcriptome Profiles of Human HaCaT Cells in Response to Gynostemma pentaphyllum Extracts Obtained Using Three Independent Methods by RNA Sequencing

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recommendations! Published in 2023 at "Life"

DOI: 10.3390/life13020423

Abstract: Gynostemma pentaphyllum (GP) is widely used in herbal medicine. In this study, we developed a method for the large-scale production of GP cells using plant tissue culture techniques combined with bioreactors. Six metabolites (uridine, adenosine,… read more here.

Keywords: three independent; independent methods; gynostemma pentaphyllum; using three ... See more keywords