Facile synthesis of the glucosylceramide synthase inhibitor GZ667161
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DOI: 10.1016/j.tetlet.2020.152352
Abstract: Abstract GZ667161 (GZ-161) is a quinuclidine-based small molecule inhibitor of the lysosomal enzyme glucosylceramide synthase. It represents an important tool molecule for studying the contribution of glycosphingolipids to disease pathology in lysosomal storage disorders such… read more here.
Keywords: gz667161; inhibitor; synthesis; glucosylceramide synthase ... See more keywords