Granzyme K - A novel marker to identify the presence and rupture of abdominal aortic aneurysm.
Sign Up to like & getrecommendations! Published in 2021 at "International journal of cardiology"
DOI: 10.1016/j.ijcard.2021.06.014
Abstract: BACKGROUND Immune inflammatory dysfunction is a hallmark of abdominal aortic aneurysm (AAA). Granzyme K (GZMK) is involved in the regulation of inflammation. However, the correlation between GZMK expression and AAA risk remains unknown. METHODS This… read more here.
Keywords: serum gzmk; gzmk expression; gzmk; rupture ... See more keywords
Granzyme K initiates IL-6 and IL-8 release from epithelial cells by activating protease-activated receptor 2
Sign Up to like & getrecommendations! Published in 2022 at "PLoS ONE"
DOI: 10.1371/journal.pone.0270584
Abstract: Granzyme K (GzmK) is a tryptic member of the granzyme family of chymotrypsin-like serine proteases produced by cells of the immune system. Previous studies have indicated that GzmK activates protease-activated receptor 1 (PAR1) enhancing activation… read more here.
Keywords: protease activated; granzyme; gzmk; receptor ... See more keywords