Quercetin enhances the antitumor activity of trichostatin A through up-regulation of p300 protein expression in p53 null cancer cells.
Sign Up to like & getrecommendations! Published in 2019 at "Chemico-biological interactions"
DOI: 10.1016/j.cbi.2019.04.006
Abstract: In the present study, we investigated the p53-independent mechanism by which quercetin (Q) increased apoptosis in human lung cancer H1299 cells exposed to trichostatin A (TSA), a histone deacetylase inhibitor. We also investigated the role of… read more here.
Keywords: h1299 cells; protein expression; expression; apoptosis ... See more keywords
PCAF-mediated acetylation of Lin28B increases let-7 biogenesis in lung adenocarcinoma H1299 cells
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DOI: 10.1186/s12885-017-3959-0
Abstract: BackgroundLin28B and its paralog Lin28A are small RNA binding proteins that have similar inhibitory effects, although they target separate steps in the maturation of let-7 miRNAs in mammalian cells. Because Lin28B participates in the promotion… read more here.
Keywords: h1299 cells; lung adenocarcinoma; pcaf; h1299 ... See more keywords
Citronellol Induces Necroptosis of Human Lung Cancer Cells via TNF-α Pathway and Reactive Oxygen Species Accumulation
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DOI: 10.21873/invivo.11590
Abstract: Background/Aim: Our current study aimed to determine the molecular mechanisms of citronellol-induced cell death and ROS accumulation in non-small cell lung cancer (NCI-H1299 cells) and also compare the anticancer effects of citronellol and EOPC. Materials… read more here.
Keywords: h1299 cells; citronellol; nci h1299; lung cancer ... See more keywords
Combination Therapy of Chloroquine and C2-Ceramide Enhances Cytotoxicity in Lung Cancer H460 and H1299 Cells
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DOI: 10.3390/cancers11030370
Abstract: Non-small cell lung cancer (NSCLC) is a type of malignant cancer, and 85% of metastatic NSCLC patients have a poor prognosis. C2-ceramide induces G2/M phase arrest and cytotoxicity in NSCLC cells. In this study, the… read more here.
Keywords: h1299 cells; h460 h1299; ceramide; lung cancer ... See more keywords
Effect of AGER on the biological behavior of non-small cell lung cancer H1299 cells
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DOI: 10.3892/mmr.2020.11176
Abstract: Advanced glycosylation end-product specific receptor (AGER) is a multi-ligand cell surface receptor abnormally expressed in lung cancer, and is a member of the immunoglobulin superfamily. Therefore, this study aimed to explore the effect of AGER… read more here.
Keywords: h1299 cells; expression; cancer; cell ... See more keywords
Preparation of Nereid oligopeptide and investigation of the mechanism underlying the induction of apoptosis in human lung cancer H1299 cells
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Medicine Reports"
DOI: 10.3892/mmr.2022.12710
Abstract: In the present study, oligopeptides from Nereid (Perinereis aibuhitensis) were prepared via enzymatic hydrolysis, and the mechanism underlying the induction of apoptosis in H1299 cells was investigated. According to the analysis of the inhibition rate… read more here.
Keywords: h1299; mechanism underlying; induction apoptosis; h1299 cells ... See more keywords
miR-10a increases the cisplatin resistance of lung adenocarcinoma circulating tumor cells via targeting PIK3CA in the PI3K/Akt pathway
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DOI: 10.3892/or.2020.7547
Abstract: Circulating tumor cells (CTCs) that are shed from the primary tumor invade the blood stream or surrounding parenchyma to form new tumors. The present study aimed to explore the underlying mechanism of cisplatin resistance in… read more here.
Keywords: h1299 cells; cisplatin; resistance; mir 10a ... See more keywords