Evolution patterns of Peg3 and H19-ICR.
Sign Up to like & getrecommendations! Published in 2018 at "Genomics"
DOI: 10.1016/j.ygeno.2018.11.025
Abstract: Mammalian imprinted domains are regulated through small genomic regions termed Imprinting Control Regions (ICRs). In the current study, the evolution patterns of the ICRs of Peg3 and H19-imprinted domains were analyzed using the genomic sequences… read more here.
Keywords: h19 icr; peg3 h19; binding sites; tandem repeats ... See more keywords
Identification of responsible sequences which mutations cause maternal H19-ICR hypermethylation with Beckwith–Wiedemann syndrome-like overgrowth
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DOI: 10.1038/s42003-024-07323-x
Abstract: Beckwith-Wiedemann syndrome (BWS) is caused by a gain of methylation (GOM) at the imprinting control region within the Igf2-H19 domain on the maternal allele (H19-ICR GOM). Mutations in the binding sites of several transcription factors… read more here.
Keywords: icr; like overgrowth; h19 icr; gom ... See more keywords