Molecular and epidemiological analysis of pandemic and post‐pandemic influenza A(H1N1)pdm09 virus from central India
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Medical Virology"
DOI: 10.1002/jmv.24982
Abstract: Influenza A(H1N1)pdm09 virus pandemic struck India in 2009 and continues to cause outbreaks in its post‐pandemic phase. Diminutive information is available about influenza A(H1N1)pdm09 from central India. This observational study presents epidemiological and molecular findings… read more here.
Keywords: influenza h1n1; h1n1 pdm09; central india;
Genetic and antigenic characterization of influenza A(H1N1)pdm09 in Yantai, China, during the 2009–2017 influenza season
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Medical Virology"
DOI: 10.1002/jmv.25328
Abstract: This study was performed to determine the antigenic and genetic characteristics and evaluate potential vaccine efficacy of influenza A (H1N1)pdm09 in Yantai from August 2009 to August 2017. read more here.
Keywords: influenza h1n1; h1n1 pdm09; influenza; pdm09 yantai ... See more keywords
Molecular analysis of amantadine-resistant influenza A (H1N1 pdm09) virus isolated from slum dwellers of Dhaka, Bangladesh
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DOI: 10.1007/s11262-017-1447-x
Abstract: Influenza is a highly contagious viral infection associated with excessive hospitalizations and deaths throughout the world. Continuous antigenic shift and drift is not only responsible for this devastating effect of influenza but also causes ineffectiveness… read more here.
Keywords: virus; h1n1 pdm09; influenza; amantadine drug ... See more keywords
Influenza A(H1N1)pdm09 virus exhibiting reduced susceptibility to baloxavir due to a PA E23K substitution detected from a child without baloxavir treatment.
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DOI: 10.1016/j.antiviral.2020.104828
Abstract: Human-to-human transmission of PA I38 mutant influenza A(H3N2) viruses with reduced baloxavir susceptibility has been reported in Japan. In December 2019, we detected a PA E23K mutant A(H1N1)pdm09 virus from a child without baloxavir treatment.… read more here.
Keywords: susceptibility; h1n1 pdm09; influenza; pdm09 virus ... See more keywords
Evaluation of correlates of protection against influenza A(H3N2) and A(H1N1)pdm09 infection: Applications to the hospitalized patient population.
Sign Up to like & getrecommendations! Published in 2019 at "Vaccine"
DOI: 10.1016/j.vaccine.2019.01.055
Abstract: BACKGROUND Influenza vaccines are important for prevention of influenza-associated hospitalization. However, the effectiveness of influenza vaccines can vary by year and influenza type and subtype and mechanisms underlying this variation are incompletely understood. Assessments of… read more here.
Keywords: correlates protection; pdm09 infection; h1n1 pdm09; infection ... See more keywords
An indirect comparison meta-analysis of AS03 and MF59 adjuvants in pandemic influenza A(H1N1)pdm09 vaccines.
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DOI: 10.1016/j.vaccine.2019.06.039
Abstract: BACKGROUND Although oil-in-water adjuvants improve pandemic influenza vaccine efficacy, AS03 versus MF59 adjuvant comparisons in A(H1N1)pdm09 pandemic vaccines are lacking. METHODS We conducted an indirect-comparison meta-analysis extracting published data from randomised controlled trials in literature… read more here.
Keywords: h1n1 pdm09; mf59; pandemic influenza; as03 mf59 ... See more keywords
Influenza A(H1N1)pdm09 outbreak detected in inter-seasonal months during the surveillance of influenza-like illness in Pune, India, 2012–2015
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DOI: 10.1017/s0950268817000553
Abstract: SUMMARY An outbreak of influenza A(H1N1)pdm09 was detected during the ongoing community-based surveillance of influenza-like illness (ILI). Among reported 119 influenza A(H1N1)pdm09 cases (59 cases in the year 2012 and 60 cases in 2015) in… read more here.
Keywords: 2012 2015; influenza h1n1; h1n1 pdm09; influenza ... See more keywords
Characterizing genetic and antigenic divergence from vaccine strain of influenza A and B viruses circulating in Thailand, 2017–2020
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DOI: 10.1038/s41598-020-80895-w
Abstract: We monitored the circulating strains and genetic variation among seasonal influenza A and B viruses in Thailand between July 2017 and March 2020. The hemagglutinin gene was amplified and sequenced. We identified amino acid (AA)… read more here.
Keywords: vaccine strain; influenza viruses; h1n1 pdm09; influenza ... See more keywords
Effectiveness of the trivalent MF59 adjuvated influenza vaccine in preventing hospitalization due to influenza B and A(H1N1)pdm09 viruses in the elderly in Italy, 2017 – 2018 season
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DOI: 10.1080/14760584.2019.1627206
Abstract: ABSTRACT Background: Evidence on influenza vaccine effectiveness (VE) in preventing mortality and morbidity in the elderly is weak. Our aim was to measure the VE against severe outcomes in the elderly. Methods: We conducted a… read more here.
Keywords: vaccine; h1n1 pdm09; pdm09 viruses; influenza vaccine ... See more keywords
723. Validation of a Wild-Type Influenza A/Texas-Like H3N2 Human Challenge Model with Comparison to the Validated A(H1N1)pdm09 Model
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DOI: 10.1093/ofid/ofy210.730
Abstract: Abstract Background Healthy volunteer challenge studies provide an opportunity to better understand influenza pathogenesis and correlates of protection. The development of vaccines and therapeutics has relied on these studies as will future universal vaccine candidates.… read more here.
Keywords: h3n2; challenge; h1n1 pdm09; model ... See more keywords
Histological characteristics of matrix metalloproteinase‐9 and tissue inhibitor of metalloproteinases‐1 in asthmatic murine model during A(H1N1)pdm09 infection
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DOI: 10.1111/pin.13268
Abstract: Pandemic influenza virus A(H1N1)pdm09 infection occurred in healthy children and young adults, but asthmatic patients presented more rapid progression of respiratory distress and plastic bronchitis. To investigate the pathogenesis of worsening respiratory symptoms after A(H1N1)pdm09… read more here.
Keywords: pdm09 infection; h1n1; h1n1 pdm09; tissue ... See more keywords