Articles with "h2b ubiquitylations" as a keyword



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The Effects of Histone H2B Ubiquitylations on the Nucleosome Structure and Internucleosomal Interactions.

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Published in 2022 at "Biochemistry"

DOI: 10.1021/acs.biochem.2c00422

Abstract: Eukaryotic gene compaction takes place at multiple levels to package DNA to chromatin and chromosomes. Two of the most fundamental levels of DNA packaging are at the nucleosome and dinucleosome stacks. The nucleosome is the… read more here.

Keywords: structure; histone h2b; h2b ubiquitylations; structure internucleosomal ... See more keywords
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Effects of Histone H2B Ubiquitylations and H3K79me3 on Transcription Elongation.

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Published in 2023 at "ACS chemical biology"

DOI: 10.1021/acschembio.2c00887

Abstract: Post-translational modifications of histone proteins often mediate gene regulation by altering the global and local stability of the nucleosome, the basic gene-packing unit of eukaryotes. We employed semisynthetic approaches to introduce histone H2B ubiquitylations at… read more here.

Keywords: histone h2b; transcription; transcription elongation; h2b ubiquitylations ... See more keywords