H2 as a fuel for flavin- and H2O2-dependent biocatalytic reactions.
Sign Up to like & getrecommendations! Published in 2020 at "Chemical communications"
DOI: 10.1039/d0cc03229h
Abstract: The soluble hydrogenase from Ralstonia eutropha provides an atom efficient regeneration system for reduced flavin cofactors using H2 as an electron source. We demonstrated this system for highly selective ene-reductase-catalyzed C[double bond, length as m-dash]C-double… read more here.
Keywords: biocatalytic reactions; dependent biocatalytic; flavin h2o2; fuel flavin ... See more keywords
Selective hydroxylation of naphthalene using the H2O2-dependent engineered P450BM3 driven by dual-functional small molecules
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Porphyrins and Phthalocyanines"
DOI: 10.1142/s108842461850061x
Abstract: We herein report the H2O2-dependent selective hydroxylation of naphthalene catalyzed by engineered P450BM3 with the assistance of dual-functional small molecules (DFSMs). The mutation at position 268 significantly improved the hydroxylation activity of P450BM3, which is… read more here.
Keywords: hydroxylation; h2o2 dependent; dual functional; engineered p450bm3 ... See more keywords