O2⋅- and H2O2-Mediated Disruption of Fe Metabolism Causes the Differential Susceptibility of NSCLC and GBM Cancer Cells to Pharmacological Ascorbate.
Sign Up to like & getrecommendations! Published in 2017 at "Cancer cell"
DOI: 10.1016/j.ccell.2017.07.008
Abstract: Joshua D. Schoenfeld1, Zita A. Sibenaller1, Kranti A. Mapuskar1, Brett A. Wagner1, Kimberly L. Cramer-Morales1, Muhammad Furqan2, Sonia Sandhu2, Thomas L. Carlisle2, Mark C. Smith1, Taher Abu Hejleh2, Daniel J. Berg2, Jun Zhang2, John Keech3,… read more here.
Keywords: metabolism causes; h2o2 mediated; causes differential; mediated disruption ... See more keywords
Screening compound libraries for H2O2-mediated cancer therapeutics using a peroxiredoxin-based sensor.
Sign Up to like & getrecommendations! Published in 2021 at "Cell chemical biology"
DOI: 10.1016/j.chembiol.2021.09.003
Abstract: Compounds that modulate H2O2 reaction networks have applications as targeted cancer therapeutics, as a subset of cancers exhibit sensitivity to this redox signal. Previous studies to identify therapeutics that induce oxidants have relied upon probes… read more here.
Keywords: peroxiredoxin; h2o2 mediated; screening compound; cancer therapeutics ... See more keywords
Hypoxia enhances H2O2-mediated upregulation of hepcidin: Evidence for NOX4-mediated iron regulation
Sign Up to like & getrecommendations! Published in 2018 at "Redox Biology"
DOI: 10.1016/j.redox.2018.02.005
Abstract: The exact regulation of the liver-secreted peptide hepcidin, the key regulator of systemic iron homeostasis, is still poorly understood. It is potently induced by iron, inflammation, cytokines or H2O2 but conflicting results have been reported… read more here.
Keywords: h2o2 mediated; hepcidin; hypoxia; iron ... See more keywords
Partial-Redox-Promoted Mn Cycling of Mn(II)-Doped Heterogeneous Catalyst for Efficient H2O2-Mediated Oxidation.
Sign Up to like & getrecommendations! Published in 2017 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.6b12445
Abstract: The development of a heterogeneous catalyst with high catalytic activity and durability for H2O2-mediated oxidation is one of the most important industrial and environmental issues. In this study, a Mn(II)-doped TiO2 heterogeneous catalyst was developed… read more here.
Keywords: mediated oxidation; catalyst; heterogeneous catalyst; h2o2 mediated ... See more keywords
Pseudomonas aeruginosa Dps (PA0962) Functions in H2O2 Mediated Oxidative Stress Defense and Exhibits In Vitro DNA Cleaving Activity
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24054669
Abstract: We report the structural, biochemical, and functional characterization of the product of gene PA0962 from Pseudomonas aeruginosa PAO1. The protein, termed Pa Dps, adopts the Dps subunit fold and oligomerizes into a nearly spherical 12-mer… read more here.
Keywords: mediated oxidative; dna; pseudomonas aeruginosa; oxidative stress ... See more keywords