Amitriptyline functionally antagonizes cardiac H2 histamine receptors in transgenic mice and human atria
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DOI: 10.1007/s00210-021-02065-7
Abstract: We have previously shown that histamine (2-(1H-imidazol-4-yl)ethanamine) exerted concentration-dependent positive inotropic effects (PIE) or positive chronotropic effects (PCE) on isolated left and right atria, respectively, of transgenic (H2R-TG) mice that overexpress the human H2 histamine… read more here.
Keywords: h2r mice; mice human; histamine; h2r ... See more keywords