Effects of endogenous H2S production inhibition on the homeostatic responses induced by acute high-salt diet consumption.
Sign Up to like & getrecommendations! Published in 2020 at "Molecular and cellular biochemistry"
DOI: 10.1007/s11010-020-03938-w
Abstract: The gaseous modulator hydrogen sulfide (H2S) is synthesized, among other routes, by the action of cystathionine-γ-lyase (CSE) and importantly participates in body fluid homeostasis. Therefore, the present study aimed to evaluate the participation of H2S… read more here.
Keywords: homeostatic responses; production; effects endogenous; inhibition ... See more keywords
E2β Stimulates Ovine Uterine Artery Endothelial Cell H2S Production in vitro by Estrogen Receptor-Dependent Upregulation of Cystathionine β-Synthase and Cystathionine γ -Lyase Expression†
Sign Up to like & getrecommendations! Published in 2018 at "Biology of Reproduction"
DOI: 10.1093/biolre/ioy207
Abstract: Abstract Endogenous hydrogen sulfide (H2S) is a potent vasodilator and proangiogenic second messenger synthesized from L-cysteine by cystathionine β-synthase (CBS) and cystathionine γ -lyase (CTH). Estrogens are potent vasodilators that stimulate H2S biosynthesis in uterine… read more here.
Keywords: cbs cth; cystathionine; cth; h2s production ... See more keywords
ERα/ERβ-directed CBS transcription mediates E2β-stimulated hUAEC H2S production.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of molecular endocrinology"
DOI: 10.1530/jme-22-0175
Abstract: Elevated endogenous estrogens stimulate human uterine artery endothelial cell (hUAEC) hydrogen sulfide (H2S) production by selectively upregulating the expression of H2S synthesizing enzyme cystathionine β-synthase (CBS), but the underlying mechanisms are underdetermined. We hypothesized that… read more here.
Keywords: promoter; huaec h2s; transcription; h2s production ... See more keywords
The Capacity to Produce Hydrogen Sulfide (H2S) via Cysteine Degradation Is Ubiquitous in the Human Gut Microbiome
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2021.705583
Abstract: As one of the three mammalian gasotransmitters, hydrogen sulfide (H2S) plays a major role in maintaining physiological homeostasis. Endogenously produced H2S plays numerous beneficial roles including mediating vasodilation and conferring neuroprotection. Due to its high… read more here.
Keywords: h2s; gut; cysteine degradation; cysteine ... See more keywords
Genes Responsible for H2S Production and Metabolism Are Involved in Learning and Memory in Drosophila melanogaster
Sign Up to like & getrecommendations! Published in 2022 at "Biomolecules"
DOI: 10.3390/biom12060751
Abstract: The gasotransmitter hydrogen sulfide (H2S) produced by the transsulfuration pathway (TSP) is an important biological mediator, involved in many physiological and pathological processes in multiple higher organisms, including humans. Cystathionine-β-synthase (CBS) and cystathionine-γ-lyase (CSE) enzymes… read more here.
Keywords: h2s production; memory; learning memory; drosophila melanogaster ... See more keywords
Bempedoic Acid Restores Liver H2S Production in a Female Sprague-Dawley Rat Dietary Model of Non-Alcoholic Fatty Liver
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24010473
Abstract: We previously demonstrated that treatment with BemA (bempedoic acid), an inhibitor of ATP citrate lyase, significantly reduces fatty liver in a model of liver steatosis (HFHFr—female Sprague-Dawley rat fed a high-fat high-fructose diet). Since the… read more here.
Keywords: liver; production; bempedoic acid; model ... See more keywords