Evaluation of thionolactones as a new type of hydrogen sulfide (H2S) donors for a blood pressure regulation.
Sign Up to like & getrecommendations! Published in 2021 at "Bioorganic chemistry"
DOI: 10.1016/j.bioorg.2021.104650
Abstract: Hydrogen sulfide (H2S) is a gaseous molecule that exhibits various biological effects. For example, H2S has been recognized as a blood pressure-lowering agent. Presented in this report is a new modifiable platform for H2S supply,… read more here.
Keywords: blood pressure; h2s release; sulfide h2s; h2s donors ... See more keywords
Supramolecular Tuning of H2S Release from Aromatic Peptide Amphiphile Gels: Effect of Core Unit Substituents.
Sign Up to like & getrecommendations! Published in 2019 at "Biomacromolecules"
DOI: 10.1021/acs.biomac.8b01732
Abstract: H2S is a gasotransmitter with several physiological roles, but its reactivity and short half-life in biological media make its controlled delivery difficult. For biological applications of the gas, hydrogels have the potential to deliver H2S… read more here.
Keywords: aromatic peptide; h2s release; release rates; h2s ... See more keywords
A two-photon responsive hydroxyphenylquinazolinone (HPQ)-based fluorescent organic nanoprodrug for H2S release against oxidative stress.
Sign Up to like & getrecommendations! Published in 2023 at "Chemical communications"
DOI: 10.1039/d2cc05768a
Abstract: Light-activated H2S donors have attracted considerable interest in understanding the physiological role and clinical potential of H2S, as their release is highly localized and controlled. Herein, we have evolved a new HPQ chromophore-based fluorescent organic… read more here.
Keywords: two photon; oxidative stress; based fluorescent; h2s ... See more keywords