An H3F3A K27M-mutation in a sonic hedgehog medulloblastoma.
Sign Up to like & getrecommendations! Published in 2021 at "Brain pathology"
DOI: 10.1111/bpa.13024
Abstract: Medulloblastomas are malignant embryonal brain tumours that may harbour mutations in histone-modifying genes, while mutations in histone genes have not been detected to date. We here describe the first SHH medulloblastoma with H3 K27M mutation. This… read more here.
Keywords: h3f3a k27m; medulloblastoma; mutation sonic; mutation ... See more keywords
Low Detection Rate of H3K27M Mutations in Cerebrospinal Fluid Obtained from Lumbar Puncture in Newly Diagnosed Diffuse Midline Gliomas
Sign Up to like & getrecommendations! Published in 2021 at "Diagnostics"
DOI: 10.3390/diagnostics11040681
Abstract: Recent studies have suggested the feasibility of detecting H3K27M mutations in the cerebrospinal fluid of diffuse midline glioma (DMG) patients. However, cerebrospinal fluid from patients in these studies were collected mainly during biopsy, ventriculo-peritoneal shunt… read more here.
Keywords: h3f3a k27m; lumbar puncture; fluid; diffuse midline ... See more keywords