Articles with "h3k27me3 targets" as a keyword



EZH2-Mediated H3K27me3 Targets Transcriptional Circuits of Neuronal Differentiation

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Published in 2022 at "Frontiers in Neuroscience"

DOI: 10.3389/fnins.2022.814144

Abstract: The Polycomb Repressive Complex 2 (PRC2) plays important roles in the epigenetic regulation of cellular development and differentiation through H3K27me3-dependent transcriptional repression. Aberrant PRC2 activity has been associated with cancer and neurodevelopmental disorders, particularly with… read more here.

Keywords: mediated h3k27me3; ezh2; neuronal differentiation; h3k27me3 targets ... See more keywords