Coordinated maintenance of H3K36/K27 methylation by histone demethylases preserves germ cell identity and immortality
Sign Up to like & getrecommendations! Published in 2021 at "Cell Reports"
DOI: 10.1016/j.celrep.2021.110050
Abstract: Summary Germ cells have evolved unique mechanisms to ensure the transmission of genetically and nongenetically encoded information, whose alteration compromises germ cell immortality. Chromatin factors play fundamental roles in these mechanisms. H3K36 and H3K27 methyltransferases… read more here.
Keywords: germ cell; methylation; h3k36; histone ... See more keywords
Clinical and histopathologic characterization of SETD2-mutated colorectal cancer.
Sign Up to like & getrecommendations! Published in 2022 at "Human pathology"
DOI: 10.2139/ssrn.4247261
Abstract: With the advent of next-generation sequencing (NGS), identifying and better understanding genetic mutations in cancer pathways has become more feasible. A mutation now commonly reported in NGS panels is the SETD2 gene (H3K36 trimethyltransferase). However,… read more here.
Keywords: pathology; h3k36; mutation; setd2 ... See more keywords