H3K4 Methylation Promotes Expression of Mitochondrial Dynamics Regulators to Ensure Oocyte Quality in Mice
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DOI: 10.1002/advs.202204794
Abstract: Significantly decreased H3K4 methylation in oocytes from aged mice indicates the important roles of H3K4 methylation in female reproduction. However, how H3K4 methylation regulates oocyte development remains largely unexplored. In this study, it is demonstrated… read more here.
Keywords: methylation; oocyte quality; h3k4 methylation; mice ... See more keywords
Set1 regulates telomere function via H3K4 methylation–dependent and -independent pathways and calibrates the abundance of telomere maintenance factors
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DOI: 10.1091/mbc.e22-06-0213
Abstract: Set1 is an H3K4 methyltransferase which comprises the catalytic subunit of the COMPASS complex and has been implicated in transcription, DNA repair, cell cycle control, and numerous other genomic functions. Set1 also promotes proper telomere… read more here.
Keywords: set1; methylation dependent; h3k4 methylation; telomere maintenance ... See more keywords
Inter and transgenerational impact of H3K4 methylation in neuronal homeostasis
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DOI: 10.26508/lsa.202301970
Abstract: The study highlights the importance of maintaining appropriate H3K4me3 levels to prevent negative impacts on nerve system homeostasis across generations. read more here.
Keywords: transgenerational impact; inter transgenerational; methylation neuronal; h3k4 methylation ... See more keywords