KDM4A regulates the maternal-to-zygotic transition by protecting broad H3K4me3 domains from H3K9me3 invasion in oocytes
Sign Up to like & getrecommendations! Published in 2020 at "Nature cell biology"
DOI: 10.1038/s41556-020-0494-z
Abstract: The importance of germline-inherited post-translational histone modifications on priming early mammalian development is just emerging 1 – 4 . Histone H3 lysine 9 (H3K9) trimethylation is associated with heterochromatin and gene repression during cell-fate change… read more here.
Keywords: broad h3k4me3; maternal zygotic; zygotic transition; kdm4a ... See more keywords
Long-read genome assemblies reveal a cis-regulatory landscape associated with phenotypic divergence in two sister Siniperca fish species
Sign Up to like & getrecommendations! Published in 2022 at "Zoological Research"
DOI: 10.1101/2022.11.09.515789
Abstract: Background Dissecting the genetic basis of variation in the regulation of gene expression is essential for understanding phenotypic evolution. Structural variants intersecting the cis-regulatory elements are found to cause gene expression variation in several developmental… read more here.
Keywords: h3k4me3 domains; phenotypic divergence; chuatsi scherzeri; cis regulatory ... See more keywords