Epigenetic changes occur in placentas of spontaneous and recurrent miscarriages.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of reproductive immunology"
DOI: 10.1016/j.jri.2021.103466
Abstract: BACKGROUND In contrast to genetic abnormalities which are well known to be responsible for around 50 % of human miscarriages, there is very few data about epigenetic alterations in spontaneous and recurrent miscarriages (SM, RM).… read more here.
Keywords: h3k4me3 h3k9ac; recurrent miscarriages; h3k4me3; placental tissue ... See more keywords
Gal-2 Increases H3K4me3 and H3K9ac in Trophoblasts and Preeclampsia
Sign Up to like & getrecommendations! Published in 2022 at "Biomolecules"
DOI: 10.3390/biom12050707
Abstract: Preeclampsia (PE) is a severe pregnancy disorder with a pathophysiology not yet completely understood and without curative therapy. The histone modifications H3K4me3 and H3K9ac, as well as galectin-2 (Gal-2), are known to be decreased in… read more here.
Keywords: h3k9ac trophoblasts; h3k4me3 h3k9ac; incubation gal; gal ... See more keywords