Decreased H3K9ac level of AT2R mediates the developmental origin of glomerulosclerosis induced by prenatal dexamethasone exposure in male offspring rats.
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DOI: 10.1016/j.tox.2018.10.013
Abstract: This study aimed to demonstrate that prenatal dexamethasone exposure (PDE) can induce kidney dysplasia in utero and adult glomerulosclerosis in male offspring, and to explore the underlying intrauterine programming mechanisms. Pregnant rats were subcutaneously administered… read more here.
Keywords: h3k9ac level; level; expression; dexamethasone ... See more keywords
Decreased H3K9ac level of KLF4 mediates podocyte developmental toxicity induced by prenatal caffeine exposure in male offspring rats.
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DOI: 10.1016/j.toxlet.2019.07.011
Abstract: This study aimed to verify the toxic effects of prenatal caffeine exposure (PCE) on the podocyte development in male offspring, and to explore the underlying intrauterine programming mechanisms. The pregnant rats were administered with caffeine… read more here.
Keywords: klf4; h3k9ac level; expression; male offspring ... See more keywords