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Pharmacological Characterization of 5-Substituted 1-[(2,3-dihydro-1-benzofuran-2-yl)methyl]piperazines: Novel Antagonists for the Histamine H3 and H4 Receptors with Anti-inflammatory Potential

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Published in 2017 at "Frontiers in Pharmacology"

DOI: 10.3389/fphar.2017.00825

Abstract: The histamine receptors (HRs) are traditional G protein-coupled receptors of extensive therapeutic interest. Recently, H3R and H4R subtypes have been targeted in drug discovery projects for inflammation, asthma, pain, cancer, Parkinson’s, and Alzheimer’s diseases, which… read more here.

Keywords: anti inflammatory; benzofuran methyl; dihydro benzofuran; histamine receptors ... See more keywords