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Quantifying epigenetic modulation of nucleosome breathing by high-throughput AFM imaging.

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Published in 2022 at "Biophysical journal"

DOI: 10.1016/j.bpj.2022.01.014

Abstract: Nucleosomes are the basic units of chromatin and critical to the storage and expression of eukaryotic genomes. Chromatin accessibility and gene readout are heavily regulated by epigenetic marks of which post-translational modifications of histones play… read more here.

Keywords: afm imaging; throughput afm; high throughput; h3s10phos h4k5 ... See more keywords