MiR-129-5p Protects H9c2 Cardiac Myoblasts From Hypoxia/Reoxygenation Injury by Targeting TRPM7 and Inhibiting NLRP3 Inflammasome Activation.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of cardiovascular pharmacology"
DOI: 10.1097/fjc.0000000000000991
Abstract: ABSTRACT As a biomarker for heart failure, miR-129-5p is abnormally expressed during myocardial I/R, but its specific functions and mechanisms remain largely unclear. Thus, this study explored the roles and possible mechanisms of miR-129-5p in… read more here.
Keywords: h9c2 cardiac; hypoxia reoxygenation; nlrp3 inflammasome; inflammasome activation ... See more keywords
Overexpression of Ubiquinol-Cytochrome c Reductase Core Protein 1 May Protect H9c2 Cardiac Cells by Binding with Zinc
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DOI: 10.1155/2017/1314297
Abstract: In several recent studies, proteomics analyses suggest that increase of ubiquinol-cytochrome c reductase core protein 1 (UQCRC1) is cardio-protective. However, direct evidence for this effect has not yet been obtained. Thus, the current study aimed… read more here.
Keywords: h9c2 cardiac; cytochrome reductase; cardiac cells; ubiquinol cytochrome ... See more keywords
Alterations in necroptosis during ALDH2-mediated protection against high glucose-induced H9c2 cardiac cell injury
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DOI: 10.3892/mmr.2018.9269
Abstract: The aim of the present study was to investigate whether necroptosis occurs in high glucose (HG)-induced H9c2 cardiac cell injury and whether the activation of aldehyde dehydrogenase 2 (ALDH2) can inhibit necroptosis. H9c2 cardiac cells… read more here.
Keywords: h9c2 cardiac; protein expression; expression; cell injury ... See more keywords