Zerumin A attenuates the inflammatory responses in LPS‐stimulated H9c2 cardiomyoblasts
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.22777
Abstract: Zerumin A (ZA) is one of the potential components of Curcuma amada rhizomes, and it has been shown to possess a variety of pharmacological activities. This study deals with the beneficial activity of ZA in… read more here.
Keywords: zerumin attenuates; inflammatory responses; responses lps; lps stimulated ... See more keywords
Endoplasmic Reticulum Stress Regulates Cardiomyocyte Apoptosis in Myocardial Fibrosis Development via PERK-Mediated Autophagy
Sign Up to like & getrecommendations! Published in 2020 at "Cardiovascular Toxicology"
DOI: 10.1007/s12012-020-09586-2
Abstract: Endoplasmic reticulum stress (ERS) is involved in a variety of diseases. Recently, it was found that ERS induces not only apoptosis but also autophagy. Previous studies showed that inhibition of autophagy alleviates cell injury. The… read more here.
Keywords: endoplasmic reticulum; apoptosis; reticulum stress; perk ... See more keywords
Mitochondrial OPA1 cleavage is reversibly activated by differentiation of H9c2 cardiomyoblasts.
Sign Up to like & getrecommendations! Published in 2020 at "Mitochondrion"
DOI: 10.1016/j.mito.2020.12.007
Abstract: Optic atrophy-1 (OPA1) is a dynamin-like GTPase localized to the mitochondrial inner membrane, playing key roles in inner membrane fusion and cristae maintenance. OPA1 is regulated by the mitochondrial transmembrane potential (Δψm): when Δψm is… read more here.
Keywords: inner membrane; opa1 isoforms; cleavage; opa1 cleavage ... See more keywords
Butein Ameliorates Oxidative Stress in H9c2 Cardiomyoblasts through Activation of the NRF2 Signaling Pathway
Sign Up to like & getrecommendations! Published in 2022 at "Antioxidants"
DOI: 10.3390/antiox11081430
Abstract: Oxidative stress, defined as an imbalance between reactive oxygen species (ROS) production and the antioxidant defense system, contributes to the pathogenesis of many heart diseases. Therefore, oxidative stress has been highlighted as a therapeutic target… read more here.
Keywords: stress; oxidative stress; h9c2 cardiomyoblasts; ros production ... See more keywords