Insertion of single‐chain variable fragment (scFv) peptide linker improves surface display of influenza hemagglutinin (HA1) on non‐recombinant Lactococcus lactis
Sign Up to like & getrecommendations! Published in 2017 at "Biotechnology Progress"
DOI: 10.1002/btpr.2400
Abstract: Heterologous protein displayed on the surface of Lactococcus lactis using the binding domain of N‐acetylmuramidase (AcmA) has a potential application in vaccine delivery. In this study, we developed a non‐recombinant L. lactis surface displaying the… read more here.
Keywords: scfv peptide; ha1; ha1 acma; peptide linker ... See more keywords
Abstract 483: Hederacolchiside A1 inhibits autophagy via CTSC inhibition and inhibits growth in colon cancer
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-483
Abstract: Background: Autophagy is a normal regulatory process that degrades non-functional or unnecessary cellular components. The degradation of components provides materials for the synthesis of cellular components and, during tumor development, may provide energy. Therefore, autophagy… read more here.
Keywords: growth; hederacolchiside; colon cancer; colon ... See more keywords
Live-attenuated auxotrophic mutant of Salmonella Typhimurium expressing immunogenic HA1 protein enhances immunity and protective efficacy against H1N1 influenza virus infection.
Sign Up to like & getrecommendations! Published in 2017 at "Future microbiology"
DOI: 10.2217/fmb-2016-0190
Abstract: AIM To evaluate the efficacy of attenuated Salmonella Typhimurium (JOL912) as a live bacterial vaccine vector. MATERIALS & METHODS The JOL912 engineered to deliver HA1 protein from influenza A/Puerto Rico/8/1934 (H1N1; PR8) virus was coined… read more here.
Keywords: ha1; protective efficacy; salmonella typhimurium; ha1 protein ... See more keywords