Characterisation of the antigenic epitopes in the subunit 2 haemagglutinin of avian influenza virus H5N1
Sign Up to like & getrecommendations! Published in 2018 at "Archives of Virology"
DOI: 10.1007/s00705-018-3896-5
Abstract: Monitoring avian influenza (AI) infection and detecting silent infection in vaccinated chickens has been challenging due to the lack of effective serological diagnostic assays to differentiate between vaccinated and infected animals. Very few studies have… read more here.
Keywords: avian influenza; antigenic epitopes; h5n1; infected vaccinated ... See more keywords
Antigenicity and immunogenicity of HA2 and M2e influenza virus antigens conjugated to norovirus-like, VP1 capsid-based particles by the SpyTag/SpyCatcher technology.
Sign Up to like & getrecommendations! Published in 2021 at "Virology"
DOI: 10.1016/j.virol.2021.12.001
Abstract: Virus-like particles (VLPs) modified through different molecular technologies are employed as delivery vehicles or platforms for heterologous antigen display. We have recently created a norovirus (NoV) VLP platform, where two influenza antigens, the extracellular domain… read more here.
Keywords: ha2 m2e; influenza virus; virus; spytag spycatcher ... See more keywords
Stability of HA2 Prefusion Structure and pH-Induced Conformational Changes in the HA2 Domain of H3N2 Hemagglutinin.
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DOI: 10.1021/acs.biochem.1c00551
Abstract: Influenza hemagglutinin is the fusion protein that mediates fusion of the viral and host membranes through a large conformational change upon acidification in the developing endosome. The "spring-loaded" model has long been used to describe… read more here.
Keywords: change; prefusion; conformation; hemagglutinin ... See more keywords
Oral immunization with an attenuated Salmonella Gallinarum encoding the H9N2 haemagglutinin and M2 ectodomain induces protective immune responses against H9N2 infection in chickens
Sign Up to like & getrecommendations! Published in 2020 at "Avian Pathology"
DOI: 10.1080/03079457.2020.1775782
Abstract: ABSTRACT H9N2, a low pathogenic avian influenza virus, causes significant economic losses in the poultry industry worldwide. Herein, we describe the construction of an attenuated Salmonella Gallinarum (SG) strain for expression and delivery of H9N2… read more here.
Keywords: m2e; salmonella; immune responses; ha1 ha2 ... See more keywords