The role of human immortal skin keratinocytes‐acellular dermal matrix scaffold in skin repair and regeneration
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.28588
Abstract: In this study, we aimed to investigate the phenotypic characteristics of human immortal skin keratinocytes (HaCaT) cells and the role of acellular dermal matrix (ADM) in coculture system of HaCaT cells and ADM. Flow cytometry… read more here.
Keywords: skin; hacat cells; role; human immortal ... See more keywords
Transcriptomic profiles of human HaCaT cells in response to angelica polysaccharide
Sign Up to like & getrecommendations! Published in 2019 at "3 Biotech"
DOI: 10.1007/s13205-019-1828-z
Abstract: The aim of this study was to explore the anti-psoriatic effect and potential mechanism of Angelica polysaccharide (APS) on an in vitro HaCaT cell model. MTS assay was performed to determine whether APS has the… read more here.
Keywords: angelica polysaccharide; group; proliferation; hacat cells ... See more keywords
Sudachitin, a polymethoxyflavone from Citrus sudachi, induces apoptosis via the regulation of MAPK pathways in human keratinocyte HaCaT cells.
Sign Up to like & getrecommendations! Published in 2019 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2019.09.010
Abstract: Although we recently reported that sudachitin (5,7,4'-trihydroxy-6,8,3'-trimethoxyflavone), a polymethoxyflavone isolated from the peel of Citrus sudachi, can induce apoptosis in human keratinocyte HaCaT cells, the mechanism underlying its action remains unclear. In this study, we… read more here.
Keywords: keratinocyte hacat; citrus sudachi; polymethoxyflavone; hacat cells ... See more keywords
Protective roles of NRF2 signaling pathway in cobalt chloride‐induced hypoxic cytotoxicity in human HaCaT keratinocytes
Sign Up to like & getrecommendations! Published in 2018 at "Toxicology and Applied Pharmacology"
DOI: 10.1016/j.taap.2018.06.030
Abstract: ABSTRACT Hypoxia is a key pathological process involved in many cutaneous diseases. Nuclear factor E2‐related factor 2 (NRF2) is a central regulator of antioxidant response element (ARE)‐dependent transcription and plays a pivotal role in the… read more here.
Keywords: nrf2 signaling; signaling pathway; hacat cells; hacat ... See more keywords
MicroRNA-26a inhibits wound healing through decreased keratinocytes migration by regulating ITGA5 through PI3K/AKT signaling pathway
Sign Up to like & getrecommendations! Published in 2020 at "Bioscience Reports"
DOI: 10.1042/bsr20201361
Abstract: Abstract Background: Keratinocyte migration is essential for skin wound healing and recent studies demonstrated that microRNAs (miRNAs) are involved in the differentiation, migration and apoptosis in keratinocytes. However, the function of miR-26a in wound healing… read more here.
Keywords: wound healing; itga5; mir 26a; hacat ... See more keywords
Regulation of 25‐hydroxyvitamin D‐1‐hydroxylase and 24‐hydroxylase in keratinocytes by PTH and FGF23
Sign Up to like & getrecommendations! Published in 2018 at "Experimental Dermatology"
DOI: 10.1111/exd.13760
Abstract: Renal 25‐hydroxyvitamin D‐1α‐hydroxylase (1αOHase, CYP27B1) and 24‐hydroxylase (24OHase, CYP24A1) are tightly regulated. However, little is known about the regulation of 1α(OH)ase and 24(OH)ase in extrarenal tissue such as the epidermis. This study was to determine… read more here.
Keywords: hydroxylase; ase; differentiation; hacat ... See more keywords
The Anti‐photoaging Effects of Pre‐ and Post‐treatment of Platelet‐rich Plasma on UVB‐damaged HaCaT Keratinocytes
Sign Up to like & getrecommendations! Published in 2020 at "Photochemistry and Photobiology"
DOI: 10.1111/php.13354
Abstract: Platelet‐rich plasma (PRP) has seen wide clinical use owing to its regenerative and repair abilities. Objective: To investigate the anti‐photoaging effects of pre‐ and post‐treatment of PRP on UVB‐damaged HaCaT cells. Methods: HaCaT cells were… read more here.
Keywords: uvb; treatment; pre post; hacat cells ... See more keywords
Differential regulation of surface receptor expression, proliferation, and apoptosis in HaCaT cells stimulated with interferon-γ, interleukin-4, tumor necrosis factor-α, or muramyl dipeptide
Sign Up to like & getrecommendations! Published in 2017 at "International Journal of Immunopathology and Pharmacology"
DOI: 10.1177/0394632017707611
Abstract: Keratinocytes are routinely subjected to both internal and external stimulation. This study investigates the effects of interferon gamma, interleukin-4, tumor necrosis factor alpha, and the synthetic immunomodulator muramyl dipeptide on the human keratinocyte cell line,… read more here.
Keywords: hacat; necrosis factor; tumor necrosis;
Notoginsenoside R1 protects human keratinocytes HaCaT from LPS-induced inflammatory injury by downregulation of Myd88
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Immunopathology and Pharmacology"
DOI: 10.1177/2058738419857550
Abstract: Burn injury is a gigantic challenge in public health which brings multiple negative effects to patients both in physical and spiritual aspects. Inflammation plays vital roles in the progression of burn injury, and our study… read more here.
Keywords: lps induced; cell; inflammatory injury; hacat ... See more keywords
miR-183-3p suppresses proliferation and migration of keratinocyte in psoriasis by inhibiting GAB1
Sign Up to like & getrecommendations! Published in 2020 at "Hereditas"
DOI: 10.1186/s41065-020-00138-w
Abstract: Background MicroRNAs (miRNAs) target genes involved in the hyperproliferation of keratinocytes or immune dysfunction of psoriasis. This study prospectively determined the involvement of miR-183-3p in the pathogenesis of psoriasis. Methods Differentially expressed miR-183-3p between psoriatic… read more here.
Keywords: mir 183; migration; lesional skin; psoriasis ... See more keywords
Pterostilbene's protective effects against photodamage caused by UVA/UVB irradiation.
Sign Up to like & getrecommendations! Published in 2018 at "Die Pharmazie"
DOI: 10.1691/ph.2018.8598
Abstract: Aim: The aim of this study was to further elucidate the mechanism of pterostilbene against UVA/UVB irradiation and the Nuclear factor E2-related factor 2 (Nrf2) signal pathway. Methods: A photo-damage model with UVA/UVB irradiation in… read more here.
Keywords: uva uvb; uvb irradiation; pterostilbene; hacat ... See more keywords