P107 Prevalence of haemarthrosis and clinical impact on the musculoskeletal system in people with haemophilia in the United Kingdom: evaluation of UKHCDO and haemtrack patient reported data
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DOI: 10.1093/rheumatology/keaa111.105
Abstract: Abstract Background Haemarthrosis whereby bleeding occurs within a joint is a significant feature of haemophilia. Despite the availability of prophylaxis clotting factor concentrates in the United Kingdom haemarthrosis is associated with worsening joint health and… read more here.
Keywords: united kingdom; joint health; prevalence; none ... See more keywords
Rapid inflammation and early degeneration of bone and cartilage revealed in a time-course study of induced haemarthrosis in haemophilic rats
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DOI: 10.1093/rheumatology/key186
Abstract: OBJECTIVES Detailed knowledge of the sequential cell and tissue responses following haemarthrosis is important for a deep understanding of the pathological process initiated upon extensive bleeding into the joint causing haemophilic arthropathy (HA). The underlying… read more here.
Keywords: induced haemarthrosis; time; pathology; bone ... See more keywords
Effect of radiosynoviorthesis on the progression of arthropathy and haemarthrosis reduction in haemophilic patients
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DOI: 10.1111/hae.13326
Abstract: Repeated haemarthrosis is widely accepted as the triggering cause of synovitis and haemophilic arthropathy. A first‐line treatment of chronic synovitis is radiosynoviorthesis (RS). The aim of this study was to evaluate the RS effects on… read more here.
Keywords: reduction; progression arthropathy; haemarthrosis; effect radiosynoviorthesis ... See more keywords
Patient‐derived assessment tool using musculoskeletal ultrasound for validation of haemarthrosis
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DOI: 10.1111/hae.14591
Abstract: Haemophilia patients experience painful joint episodes which may or may not be associated with haemarthrosis. We sought to validate a questionnaire developed by the Canadian Haemophilia Society using point‐of‐care musculoskeletal ultrasound (POC MSKUS) to confirm… read more here.
Keywords: haemarthrosis; tool using; derived assessment; assessment tool ... See more keywords
Scurvy: a rare cause of haemarthrosis
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DOI: 10.1136/bcr-2021-244594
Abstract: A male in his 60s with a history of previously treated locally advanced head and neck cancer presented to the emergency department with atraumatic left knee pain and upper and lower extremity ecchymoses that had… read more here.
Keywords: haemarthrosis; rare cause; scurvy rare; left knee ... See more keywords
Absorbance or organization into ankylosis: a microarray analysis of haemarthrosis in a sheep model of temporomandibular joint trauma
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DOI: 10.1186/s12903-021-02033-w
Abstract: Background Traumatic haemarthrosis was hypothesized to be the etiology of temporomandibular (TMJ) ankylosis. Here, taking haematoma absorbance as a control, we aimed to reveal the molecular mechanisms involved in haematoma organizing into ankylosis using transcriptome… read more here.
Keywords: sheep model; absorbance; microarray; haemarthrosis ... See more keywords