Telomerase‐based therapies in haematological malignancies
Sign Up to like & getrecommendations! Published in 2022 at "Cell Biochemistry and Function"
DOI: 10.1002/cbf.3687
Abstract: Telomeres are specialized genetic structures present at the end of all eukaryotic linear chromosomes. They progressively get shortened after each cell division due to end replication problems. Telomere shortening (TS) and chromosomal instability cause apoptosis… read more here.
Keywords: cell; based therapies; haematological malignancies; therapies haematological ... See more keywords
Chinese parents’ caregiving ability for children with haematological malignancies: A latent class analysis
Sign Up to like & getrecommendations! Published in 2022 at "Nursing Open"
DOI: 10.1002/nop2.1218
Abstract: The aim of this study was to identify unobserved subgroups of Chinese parents’ caregiving ability for children with haematological malignancies and examine the associations of the latent class membership with individual characteristics. read more here.
Keywords: parents caregiving; caregiving ability; chinese parents; children haematological ... See more keywords
Association between diabetes and haematological malignancies: a population-based study
Sign Up to like & getrecommendations! Published in 2021 at "Diabetologia"
DOI: 10.1007/s00125-020-05338-7
Abstract: Contemporary data for the association of diabetes with haematological malignancies are lacking. We evaluated the risk of developing haematological malignancies and subsequent mortality in individuals with diabetes compared with those without diabetes. We conducted a… read more here.
Keywords: risk; diabetes haematological; association diabetes; association ... See more keywords
Immune-Mediated Dermatoses in Patients with Haematological Malignancies: A Comprehensive Review
Sign Up to like & getrecommendations! Published in 2020 at "American Journal of Clinical Dermatology"
DOI: 10.1007/s40257-020-00553-9
Abstract: Haematological malignancies induce important alterations of the immune system, which account for the high frequency of autoimmune complications observed in patients. Cutaneous immune-mediated diseases associated with haematological malignancies encompass a heterogeneous group of dermatoses, including,… read more here.
Keywords: mediated skin; patients haematological; haematological malignancies; review ... See more keywords
Central nervous system manifestations of systemic haematological malignancies and key differentials.
Sign Up to like & getrecommendations! Published in 2022 at "Clinical radiology"
DOI: 10.1016/j.crad.2022.01.043
Abstract: Central nervous system (CNS) involvement by haematological malignancies is uncommon, and generally associated with a poor prognosis. Neuroimaging plays a key role in the accurate diagnosis, including in the critical differentiation from other processes such… read more here.
Keywords: system manifestations; cns involvement; haematological malignancies; central nervous ... See more keywords
Heterogeneous surface-modified nanoplatforms for the targeted therapy of haematological malignancies.
Sign Up to like & getrecommendations! Published in 2019 at "Drug discovery today"
DOI: 10.1016/j.drudis.2019.10.001
Abstract: Here, we focus on nanoparticle (NP)-based platforms for the targeted therapy of haematological malignancies (HMs), providing an overview of surface-modified nanoplatforms, such as aptamer-, metal-, nucleic acid-, toxin, and peptide-modified NPs, for the efficient targeting… read more here.
Keywords: surface modified; targeted therapy; therapy haematological; haematological malignancies ... See more keywords
Measurable residual diseases in haematological malignancies: current applications and future direction
Sign Up to like & getrecommendations! Published in 2019 at "Leukemia Research"
DOI: 10.1016/s0145-2126(19)30291-7
Abstract: Minimal/ measurable residual diseases represents an independent prognostic indicator for several haematological malignancies helping to predict clinical outcome and enables for further assessment of the effectiveness of treatment. The methods of detection of MRD has… read more here.
Keywords: residual diseases; current applications; measurable residual; haematological malignancies ... See more keywords
Siltuximab and hematologic malignancies. A focus in non Hodgkin lymphoma
Sign Up to like & getrecommendations! Published in 2017 at "Expert Opinion on Investigational Drugs"
DOI: 10.1080/13543784.2017.1288213
Abstract: ABSTRACT Introduction: The role of interleukin-6 (IL-6) in tumorigenesis and in particular in haematological malignancies is crucial. On the basis of the favourable results obtained in the subset of multicentric Castleman disease (MCD), Siltuximab, a… read more here.
Keywords: focus non; hodgkin lymphoma; multiple myeloma; non hodgkin ... See more keywords
O-227 Pre-treatment semen parameters in haematological malignancies. An analysis of sequential samples
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DOI: 10.1093/humrep/deab128.051
Abstract: Does Leukaemia affect spermatogenesis more adversely than Hodgkin’s lymphoma and is the effect consistent in sequential samples? LLeukaemia is associated with a higher incidence of azoospermia, oligozoospermia and asthenozoospermia compared to Hodgkin’s lymphoma. These findings… read more here.
Keywords: hodgkin lymphoma; sequential samples; semen parameters; haematological malignancies ... See more keywords
Impact of mucositis on oral bioavailability and systemic exposure of ciprofloxacin Gram-negative infection prophylaxis in patients with haematological malignancies
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DOI: 10.1093/jac/dkac283
Abstract: Abstract Background Patients with haematological malignancies frequently endure neutropenia and gastrointestinal (GI)-mucositis after high-dose chemotherapy. In these patients, ciprofloxacin is used for Gram-negative infection prophylaxis. Objectives We investigate ciprofloxacin pharmacokinetics after oral administration in patients… read more here.
Keywords: mucositis; ciprofloxacin; patients haematological; haematological malignancies ... See more keywords
Management of adult patients with haematological malignancies in critical care
Sign Up to like & getrecommendations! Published in 2023 at "Anaesthesia"
DOI: 10.1111/anae.15955
Abstract: There are a diverse range of haematological malignancies with varying clinical presentations and prognoses. Patients with haematological malignancy may require admission to critical care at the time of diagnosis or due to treatment related effects… read more here.
Keywords: critical care; management; patients haematological; care ... See more keywords