S1PR5 regulates NK cell responses in preventing graft‐versus‐host disease while preserving graft‐versus‐tumour activity in a murine allogeneic haematopoietic stem cell transplantation model
Sign Up to like & getrecommendations! Published in 2019 at "Hematological Oncology"
DOI: 10.1002/hon.2669
Abstract: Graft‐versus‐host disease (GVHD) remains a major complication following allogeneic haematopoietic stem cell transplantation (allo‐HSCT) leading to high transplant‐related mortality. Natural killer (NK) cells have been found to mitigate GVHD without attenuating the graft‐versus‐tumour (GVT) activity… read more here.
Keywords: graft; stem cell; s1pr5; haematopoietic stem ... See more keywords
Management of adenovirus infection in patients after haematopoietic stem cell transplantation: State‐of‐the‐art and real‐life current approach
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DOI: 10.1002/rmv.1980
Abstract: The important insights gained over the past years in diagnosis and treatment of invasive adenoviral infections provide new paradigms for the monitoring and clinical management of these life‐threatening complications. A meeting was held to discuss… read more here.
Keywords: management; stem cell; life; haematopoietic stem ... See more keywords
The current standing of autologous haematopoietic stem cell transplantation for the treatment of multiple sclerosis
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Neurology"
DOI: 10.1007/s00415-022-11063-5
Abstract: Autologous haematopoietic stem cell transplantation (aHSCT) is gaining traction as a valuable treatment option for patients affected by severe multiple sclerosis (MS), particularly the relapsing–remitting form. We describe the current literature in terms of clinical… read more here.
Keywords: stem cell; treatment; autologous haematopoietic; transplantation ... See more keywords
Plasmodium falciparum malaria skews globin gene expression balance in in-vitro haematopoietic stem cell culture system: Its implications in malaria associated anemia.
Sign Up to like & getrecommendations! Published in 2018 at "Experimental parasitology"
DOI: 10.1016/j.exppara.2018.01.003
Abstract: Understanding the pathophysiology and associated host parasite interactions of the malaria infection is the prerequisite for developing effective prevention and treatment strategies. The exact mechanism underlying malaria associated ineffective and dyserythropoiesis is not yet fully… read more here.
Keywords: malaria associated; plasmodium falciparum; expression; haematopoietic stem ... See more keywords
The serial changes in myocardial functions after paediatric haematopoietic stem cell transplantation.
Sign Up to like & getrecommendations! Published in 2022 at "Cardiology in the young"
DOI: 10.1017/s1047951122002712
Abstract: The aim of this study is to evaluate the changes in myocardial functions in children who underwent haematopoietic stem cell transplantation along with associated chemotherapy. Additionally, we evaluated the effect of baseline echocardiographic parameters on… read more here.
Keywords: haematopoietic stem; stem cell; cell transplantation;
Allogeneic haematopoietic stem cell transplant in patients with lower risk myelodysplastic syndrome: a retrospective analysis on behalf of the Chronic Malignancy Working Party of the EBMT
Sign Up to like & getrecommendations! Published in 2017 at "Bone Marrow Transplantation"
DOI: 10.1038/bmt.2017.86
Abstract: This corrects the article DOI: 10.1038/bmt.2016.266 read more here.
Keywords: patients lower; transplant patients; stem cell; allogeneic haematopoietic ... See more keywords
Haematopoietic stem cells: past, present and future
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DOI: 10.1038/cddiscovery.2017.2
Abstract: The discovery and characterisation of haematopoietic stem cells has required decades of research. The identification of adult bone marrow as a source of haematopoietic cells capable of protecting an organism from otherwise lethal irradiation led… read more here.
Keywords: cells past; stem cell; stem; stem cells ... See more keywords
Conversion of adult endothelium to immunocompetent haematopoietic stem cells
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DOI: 10.1038/nature22326
Abstract: Developmental pathways that orchestrate the fleeting transition of endothelial cells into haematopoietic stem cells remain undefined. Here we demonstrate a tractable approach for fully reprogramming adult mouse endothelial cells to haematopoietic stem cells (rEC-HSCs) through… read more here.
Keywords: adult; rec hscs; endothelial cells; stem cells ... See more keywords
Human haematopoietic stem cell lineage commitment is a continuous process
Sign Up to like & getrecommendations! Published in 2017 at "Nature cell biology"
DOI: 10.1038/ncb3493
Abstract: Blood formation is believed to occur through stepwise progression of haematopoietic stem cells (HSCs) following a tree-like hierarchy of oligo-, bi- and unipotent progenitors. However, this model is based on the analysis of predefined flow-sorted… read more here.
Keywords: lineage commitment; cell; haematopoietic stem; human haematopoietic ... See more keywords
Gut microbiota injury in allogeneic haematopoietic stem cell transplantation
Sign Up to like & getrecommendations! Published in 2018 at "Nature Reviews Cancer"
DOI: 10.1038/nrc.2018.10
Abstract: Allogeneic haematopoietic stem cell transplantation (allo-HSCT) is considered to be the strongest curative immunotherapy for various malignancies (primarily, but not limited to, haematologic malignancies). However, application of allo-HSCT is limited owing to its life-threatening major… read more here.
Keywords: allo hsct; cell transplantation; stem cell; allogeneic haematopoietic ... See more keywords
Outcomes of haploidentical haematopoietic stem cell transplantation for paroxysmal nocturnal haemoglobinuria
Sign Up to like & getrecommendations! Published in 2019 at "Bone Marrow Transplantation"
DOI: 10.1038/s41409-019-0751-6
Abstract: Allogeneic haematopoietic stem cell transplantation (alloHSCT) might be used in paroxysmal nocturnal haemoglobinuria (PNH) patients outside open clinical trials assessing the complement inhibitors and the presence of a PNH clone with evidence of clonal evolution… read more here.
Keywords: range; cell transplantation; stem cell; transplantation ... See more keywords