Fatal haemolytic transfusion reaction due to anti‐Ena and identification of a novel GYPA c.295delG variant in a Thai family
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DOI: 10.1111/vox.13358
Abstract: High‐frequency antigen Ena (MNS 28) is expressed on glycophorin A (GPA). En(a−) individuals can form anti‐Ena when exposed to GPA. A Thai patient formed an antibody that reacted against all reagent red blood cells (RBCs).… read more here.
Keywords: transfusion reaction; haemolytic transfusion; anti ena; fatal haemolytic ... See more keywords
Basophil activation test for allergic and febrile non‐haemolytic transfusion reactions among paediatric patients with haematological or oncological disease
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DOI: 10.1111/vox.13365
Abstract: Allergic transfusion reactions (ATRs) and febrile non‐haemolytic transfusion reactions (FNHTRs) are common, although their mechanisms remain unclear. Immunoglobulin E (IgE)‐mediated type I hypersensitivity may be involved in the pathogenesis of ATR. A basophil activation test… read more here.
Keywords: haemolytic transfusion; basophil activation; febrile non; non haemolytic ... See more keywords
The complexities of transfusion reactions: Coexistence of a delayed haemolytic transfusion reaction and post‐transfusion purpura
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DOI: 10.1111/vox.13381
Abstract: Immune‐mediated acute or delayed transfusion reactions occur when there is immunological incompatibility between transfused blood products and recipient's antibodies. Acute haemolytic transfusion reactions occur within 24 h and are delayed after 24 h up to 10 days following… read more here.
Keywords: haemolytic transfusion; post transfusion; transfusion purpura; delayed haemolytic ... See more keywords
Analysis of haemovigilance reports reveals 12.5% of acute haemolytic transfusion reactions are attributed to antibodies to low‐incidence antigens
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DOI: 10.1111/vox.70068
Abstract: Many transfusion centres no longer perform an antiglobulin crossmatch on patients without clinically significant red cell alloantibodies, but instead use an abbreviated crossmatch. This policy brings many benefits but has an acknowledged risk of haemolytic… read more here.
Keywords: haemolytic transfusion; low incidence; incidence antigens; transfusion reactions ... See more keywords