LAUSR

Haemolytic-uremic syndrome due to infection with adenovirus

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0 Published in 2018 at "Medicine"

DOI: 10.1097/md.0000000000009895

Abstract: Rationale: Haemolytic-uremic syndrome is a rare but serious complication of bacterial and viral infections, which is characterized by the triad of: acute renal failure, microangiopathic haemolytic anemia and thrombocytopenia, sometimes severe, requiring peritoneal dialysis. In… read more here.

Keywords: haemolytic uremic; uremic syndrome; infection; peritoneal dialysis ... See more keywords

The role of anti‐complement factor H antibodies in the development of atypical haemolytic uremic syndrome: a possible contribution to abnormality of platelet function

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0 Published in 2019 at "British Journal of Haematology"

DOI: 10.1111/bjh.16297

Abstract: Atypical haemolytic uremic syndrome (aHUS) is associated with complement system abnormality, such as production of complement factor H (CFH) autoantibodies. The growing evidence indicates complement overactivation on platelets is intimately involved in aHUS pathogenesis, besides… read more here.

Keywords: haemolytic uremic; uremic syndrome; complement factor; anti cfh ... See more keywords

Recurrent case of pregnancy-induced atypical haemolytic uremic syndrome (P-aHUS)

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0 Published in 2019 at "BMJ Case Reports"

DOI: 10.1136/bcr-2018-226571

Abstract: Pregnancy-induced atypical haemolytic uremic syndrome (P-aHUS) is a rare condition characterised by microangiopathic haemolytic anaemia, thrombocytopenia and renal failure. It accounts for approximately 7% of total HUS cases. Here, we present a case of recurrent… read more here.

Keywords: haemolytic uremic; pregnancy; pregnancy induced; atypical haemolytic ... See more keywords

Pregnancy-induced atypical haemolytic uremic syndrome: A new era with eculizumab

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0 Published in 2018 at "Obstetric Medicine"

DOI: 10.1177/1753495x17704563

Abstract: Pregnancy is a well-recognised trigger of atypical haemolytic syndrome (P-aHUS) and often occurs in the post-partum period. Similar to atypical haemolytic uremic syndrome, it carries a poor prognosis with high morbidity particularly in the form… read more here.

Keywords: haemolytic uremic; uremic syndrome; pregnancy induced; atypical haemolytic ... See more keywords

An ex vivo test to investigate genetic factors conferring susceptibility to atypical haemolytic uremic syndrome

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2 Published in 2023 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2023.1112257

Abstract: Introduction Comprehensive genetic analysis is essential to clinical care of patients with atypical haemolytic uremic syndrome (aHUS) to reinforce diagnosis, and to guide treatment. However, the characterization of complement gene variants remains challenging owing to… read more here.

Keywords: atypical haemolytic; haemolytic uremic; test; complement gene ... See more keywords