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Influence of blood group and von Willebrand factor on population pharmacokinetics and dose individualization of recombinant factor VIII in Taiwanese patients with haemophilia A

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Published in 2022 at "Haemophilia"

DOI: 10.1111/hae.14493

Abstract: The large interpatient variability in the pharmacokinetic (PK) parameters of recombinant Factor VIII (rFVIII) observed in haemophilia A hinders efficient and cost‐beneficial prophylactic regimen initiation. Identification of factors influencing the PK of rFVIII may shed… read more here.

Keywords: influence blood; recombinant factor; blood group; haemophilia influence ... See more keywords