Chemoenzymatic Total Synthesis of Haemophilus ducreyi Lipooligosaccharide Core Octasaccharides Containing Natural and Unnatural Sialic Acids.
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DOI: 10.1021/acs.orglett.3c00657
Abstract: The first total synthesis of Haemophilus ducreyi lipooligosaccharide core octasaccharides containing natural and unnatural sialic acids has been achieved by an efficient chemoenzymatic approach. A highly convergent [3 + 3] coupling strategy was developed to… read more here.
Keywords: lipooligosaccharide core; sialic acids; ducreyi lipooligosaccharide; total synthesis ... See more keywords
Multiple Class I and Class II Haemophilus ducreyi Strains Cause Cutaneous Ulcers in Children on an Endemic Island
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DOI: 10.1093/cid/ciy343
Abstract: Background Together with Treponema pallidum subspecies pertenue, Haemophilus ducreyi is a major cause of exudative cutaneous ulcers (CUs) in children. For H. ducreyi, both class I and class II strains, asymptomatic colonization, and environmental reservoirs… read more here.
Keywords: class; cutaneous ulcers; haemophilus ducreyi; island ... See more keywords
Haemophilus ducreyi in genital ulcer disease: new developments in an old disease.
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DOI: 10.1097/qco.0000000000001166
Abstract: PURPOSE OF REVIEW Haemophilus ducreyi remains an important, though often overlooked, cause of genital ulcer disease (GUD), particularly in contexts where syndromic management limits pathogen-specific diagnosis. Although its incidence has markedly declined in high-income countries,… read more here.
Keywords: ducreyi genital; genital ulcer; haemophilus ducreyi; ulcer disease ... See more keywords
Infections caused by Haemophilus ducreyi: one organism, two stories
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DOI: 10.1128/cmr.00135-24
Abstract: SUMMARY Chancroid, a sexually transmitted infection caused by Haemophilus ducreyi, is characterized by painful genital ulcers (GU) and inguinal lymphadenitis. H. ducreyi was recently described as a major cause of non-sexually transmitted cutaneous ulcers (CU)… read more here.
Keywords: one organism; organism two; caused haemophilus; haemophilus ducreyi ... See more keywords
The protein degradation system encoded by hslUV (ClpYQ) is dispensable for the virulence of Haemophilus ducreyi in human volunteers
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DOI: 10.1128/iai.00577-24
Abstract: ABSTRACT Haemophilus ducreyi causes cutaneous ulcers in children who live in yaws-endemic countries and the genital ulcer disease chancroid. In the human host, H. ducreyi resides in an abscess and may need to resist both… read more here.
Keywords: encoded hsluv; hsluv clpyq; haemophilus ducreyi; human volunteers ... See more keywords
Erratum for Brothwell et al., “Haemophilus ducreyi Infection Induces Oxidative Stress, Central Metabolic Changes, and a Mixed Pro- and Anti-Inflammatory Environment in the Human Host”
Sign Up to like & getrecommendations! Published in 2023 at "mBio"
DOI: 10.1128/mbio.03522-22
Abstract: Volume 13, no. 6, e03125-22, 2022, https://doi.org/10.1128/mBio.03125-22. Page 3, line 17 from bottom: “shown in Table 1” should read “shown in Table 1; the number of reads for samples from the pilot study are in… read more here.
Keywords: ducreyi infection; induces oxidative; infection induces; brothwell haemophilus ... See more keywords
LAMP4yaws: Treponema pallidum, Haemophilus ducreyi loop mediated isothermal amplification − protocol for a cross-sectional, observational, diagnostic accuracy study
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DOI: 10.1136/bmjopen-2021-058605
Abstract: Introduction Yaws, caused by the bacterium Treponema pallidum subsp. pertenue, is a neglected tropical disease targeted for eradication by 2030. Improved diagnostics will be essential to meet this goal. Diagnosis of yaws has relied heavily… read more here.
Keywords: pallidum; cross sectional; test; treponema pallidum ... See more keywords
Sequence typing of Haemophilus ducreyi isolated from patients in the Namatanai region of Papua New Guinea: Infections by Class I and Class II strain types differ in ulcer duration and resurgence of infection after azithromycin treatment
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DOI: 10.1371/journal.pntd.0012398
Abstract: Haemophilus ducreyi (HD) is an important cause of cutaneous ulcers in several endemic regions, including the Western Pacific Region, especially among children. An HD sequence typing on swab samples taken from 1,081 ulcers in the… read more here.
Keywords: sequence typing; class; haemophilus ducreyi; strain types ... See more keywords
Direct Whole-Genome Sequencing of Cutaneous Strains of Haemophilus ducreyi
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DOI: 10.3201/eid2404.171726
Abstract: Haemophilus ducreyi, which causes chancroid, has emerged as a cause of pediatric skin disease. Isolation of H. ducreyi in low-income settings is challenging, limiting phylogenetic investigation. Next-generation sequencing demonstrates that cutaneous strains arise from class… read more here.
Keywords: whole genome; cutaneous strains; haemophilus ducreyi; direct whole ... See more keywords