Articles with "haemophilus influenzae" as a keyword



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Haemophilus influenzae Protein D antibody suppression in a multi‐component vaccine formulation

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Published in 2022 at "FEBS Open Bio"

DOI: 10.1002/2211-5463.13498

Abstract: Nontypeable Haemophilus influenzae (NTHi) has emerged as a dominant mucosal pathogen causing acute otitis media (AOM) in children, acute sinusitis in children and adults, and acute exacerbations of chronic bronchitis in adults. Consequently, there is an… read more here.

Keywords: vaccine formulation; haemophilus influenzae; vaccine; antibody ... See more keywords
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Anti‐EF‐Tu IgG titers increase with age and may contribute to protection against the respiratory pathogen Haemophilus influenzae

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Published in 2019 at "European Journal of Immunology"

DOI: 10.1002/eji.201847871

Abstract: Non‐typeable Haemophilus influenzae (NTHi) is a pathogen that commonly colonizes the nasopharynx of preschool children, causing opportunistic infections including acute otitis media (AOM). Patients suffering from chronic obstructive pulmonary disease (COPD) are persistently colonized with… read more here.

Keywords: pathogen; haemophilus influenzae; igg; age ... See more keywords
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In vitro assembly of Haemophilus influenzae adhesin transmembrane domain and studies on the electrostatic repulsion at the interface

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Published in 2019 at "Biophysical Reviews"

DOI: 10.1007/s12551-019-00535-0

Abstract: Haemophilus influenzae adhesin (Hia) belongs to the trimeric autotransporter family, and it mediates the adherence of these bacteria to the epithelial cells of host organisms. Hia is composed of the passenger domain, which is a… read more here.

Keywords: haemophilus influenzae; transmembrane domain; influenzae adhesin; electrostatic repulsion ... See more keywords
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Selective Inhibition of Sialic Acid-Based Molecular Mimicry in Haemophilus influenzae Abrogates Serum Resistance.

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Published in 2018 at "Cell chemical biology"

DOI: 10.1016/j.chembiol.2018.05.018

Abstract: Pathogens such as non-typeable Haemophilus influenzae (NTHi) evade the immune system by presenting host-derived sialic acids. NTHi cannot synthesize sialic acids and therefore needs to utilize sialic acids originating from host tissue. Here we report… read more here.

Keywords: acid based; haemophilus influenzae; sialic acids; sialic acid ... See more keywords
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Learning from –omics strategies applied to uncover Haemophilus influenzae host-pathogen interactions: Current status and perspectives

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Published in 2021 at "Computational and Structural Biotechnology Journal"

DOI: 10.1016/j.csbj.2021.05.026

Abstract: Haemophilus influenzae has contributed to key bacterial genome sequencing hallmarks, as being not only the first bacterium to be genome-sequenced, but also starring the first genome-wide analysis of chromosomes directly transformed with DNA from a… read more here.

Keywords: influenzae host; pathogen; influenzae; haemophilus influenzae ... See more keywords
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Encapsulated pleural effusion due to Haemophilus influenzae biotype II in a child with trisomy 21: A case report and literature review

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Published in 2017 at "IDCases"

DOI: 10.1016/j.idcr.2017.09.007

Abstract: Highlights • This is the second case report of pediatric encapsulated pleural effusion (EPE) due to Haemophilus influenzae.• We represent typical images of chest X-P, CT, echography to find the EPE.• Nontypeable H. influenzae was… read more here.

Keywords: haemophilus influenzae; pleural effusion; due haemophilus; encapsulated pleural ... See more keywords
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Haemophilus influenzae type b meningitis in a vaccinated and immunocompetent child.

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Published in 2017 at "Journal of infection and public health"

DOI: 10.1016/j.jiph.2016.06.001

Abstract: Invasive Haemophilus influenzae type b (Hib) disease decreased dramatically after the introduction of conjugate vaccine in routine immunization schedules. We report a case of a fifteen-months-old girl, previously healthy and vaccinated, admitted in the emergency… read more here.

Keywords: meningitis; hib disease; haemophilus influenzae; influenzae type ... See more keywords
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Rapid and direct molecular detection of Streptococcus pneumoniae and Haemophilus influenzae isolated in oropharynx and nasal cavity of children

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Published in 2020 at "New Microbes and New Infections"

DOI: 10.1016/j.nmni.2019.100632

Abstract: There is a direct correlation between asymptomatic oropharyngeal colonization by pathogenic bacteria and the prevalence of paediatric respiratory infections. Streptococcus pneumoniae and Haemophilus influenzae are common cause of serious bacterial infections such as meningitis in… read more here.

Keywords: pneumoniae haemophilus; pneumoniae influenzae; influenzae; haemophilus influenzae ... See more keywords
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Nontypeable Haemophilus influenzae (NTHi).

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Published in 2018 at "Trends in microbiology"

DOI: 10.1016/j.tim.2018.05.001

Abstract: In this infographic the diseases caused by nontypeable Haemophilus influenzae (NTHi), including otitis media, are discussed. Encapsulated type b Haemophilus influenzae (Hib) was responsible for most of the invasive disease (meningitis) prior to the use… read more here.

Keywords: influenzae nthi; nontypeable haemophilus; haemophilus influenzae;
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Nonlocal Effects of Antibiotic-Resistance-Causing Mutations Reveal an Alternative Region for Targeting on FtsW-Penicillin-Binding Protein 3 Complex of Haemophilus influenzae

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Published in 2023 at "Journal of chemical information and modeling"

DOI: 10.1021/acs.jcim.3c00127

Abstract: Currently prescribed antibiotics target the catalytic sites of wild-type bacterial proteins; however, bacteria adopt mutations at this site, eventually leading to the emergence of resistance. Therefore, the identification of alternative drug binding sites is crucial,… read more here.

Keywords: binding protein; haemophilus influenzae; resistance causing; resistance ... See more keywords
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Employment of Iron-Binding Protein from Haemophilus influenzae in Functional Nanopipettes for Iron Monitoring.

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Published in 2019 at "ACS chemical neuroscience"

DOI: 10.1021/acschemneuro.8b00263

Abstract: Because of the serious neurologic consequences of iron deficiency and iron excess in the brain, interest in the iron status of the central nervous system has increased significantly in the past decade. While iron plays… read more here.

Keywords: haemophilus influenzae; employment iron; iron binding; protein haemophilus ... See more keywords